The impact of COVID-19 disease on platelets and coagulation

GD Wool, JL Miller - Pathobiology, 2021 - karger.com
Abstract Coronavirus disease 2019 (COVID-19) causes a spectrum of disease; some
patients develop a severe proinflammatory state which can be associated with a unique …

[HTML][HTML] Large and small platelets—(When) do they differ?

S Handtke, T Thiele - Journal of Thrombosis and Haemostasis, 2020 - Elsevier
Platelets are most important in providing cellular hemostasis but also take part in
inflammation and immune processes. Increased platelet size has been regarded as a …

Platelet proteomes, pathways, and phenotypes as informants of vascular wellness and disease

JE Aslan - Arteriosclerosis, thrombosis, and vascular biology, 2021 - Am Heart Assoc
Platelets rapidly undergo responsive transitions in form and function to repair vascular
endothelium and mediate hemostasis. In contrast, heterogeneous platelet subpopulations …

Molecular proteomics and signalling of human platelets in health and disease

J Huang, P Zhang, FA Solari, A Sickmann… - International Journal of …, 2021 - mdpi.com
Platelets are small anucleate blood cells that play vital roles in haemostasis and thrombosis,
besides other physiological and pathophysiological processes. These roles are tightly …

[HTML][HTML] Proteome and functional decline as platelets age in the circulation

HE Allan, MA Hayman, S Marcone, MV Chan… - Journal of Thrombosis …, 2021 - Elsevier
Background Platelets circulate in the blood of healthy individuals for approximately 7–10
days regulated by finely balanced processes of production and destruction. As platelets are …

Hyperthrombotic milieu in COVID-19 patients

MH Kamel, W Yin, C Zavaro, JM Francis, VC Chitalia - Cells, 2020 - mdpi.com
COVID-19 infection has protean systemic manifestations. Experience from previous
coronavirus outbreaks, including the current SARS-CoV-2, has shown an augmented risk of …

[HTML][HTML] Platelet ageing: a review

HE Allan, A Vadgama, PC Armstrong, TD Warner - Thrombosis Research, 2023 - Elsevier
Platelet ageing is an area of research which has gained much interest in recent years.
Newly formed platelets, often referred to as reticulated platelets, young platelets or immature …

Platelet distribution width is associated with P-selectin dependent platelet function: results from the Moli-family cohort study

B Izzi, A Gialluisi, F Gianfagna, S Orlandi, A De Curtis… - Cells, 2021 - mdpi.com
Defined as an index of platelet size heterogeneity, the platelet distribution width (PDW) is
still a poorly characterized marker of platelet function in (sub) clinical disease. We presently …

Association between COVID-19 diagnosis and coronary artery thrombosis: a narrative review

F Nappi, O Giacinto, O Ellouze, A Nenna… - Biomedicines, 2022 - mdpi.com
Coronavirus disease 2019 is characterized by its severe respiratory effects. Data early on
indicated an increased risk of mortality in patients with cardiovascular comorbidities. Early …

Diagnostic value of platelet indices in COVID 19 infection: a case-control study from a single tertiary care center

A Shankaralingappa, S Tummidi… - The Egyptian journal of …, 2022 - Springer
Introduction Platelets are not only involved in hemostasis and coagulation, but play a
significant role in innate immunity and inflammatory response. Excess production of …