A tripartite view of the posterior cingulate cortex
The posterior cingulate cortex (PCC) is one of the least understood regions of the cerebral
cortex. By contrast, the anterior cingulate cortex has been the subject of intensive …
cortex. By contrast, the anterior cingulate cortex has been the subject of intensive …
Anhedonia as a central factor in depression: Neural mechanisms revealed from preclinical to clinical evidence
S Wang, F Leri, SJ Rizvi - Progress in Neuro-Psychopharmacology and …, 2021 - Elsevier
Anhedonia is one of the core symptoms of major depressive disorder (MDD), which is often
inadequately treated by traditional antidepressants. The modern framework of anhedonia …
inadequately treated by traditional antidepressants. The modern framework of anhedonia …
A randomized proof-of-mechanism trial applying the 'fast-fail'approach to evaluating κ-opioid antagonism as a treatment for anhedonia
Abstract The National Institute of Mental Health (NIMH)'fast-fail'approach seeks to improve
too-often-misleading early-phase drug development methods by incorporating biomarker …
too-often-misleading early-phase drug development methods by incorporating biomarker …
Baseline brain function in the preadolescents of the ABCD Study
Abstract The Adolescent Brain Cognitive Development (ABCD) Study® is a 10-year
longitudinal study of children recruited at ages 9 and 10. A battery of neuroimaging tasks are …
longitudinal study of children recruited at ages 9 and 10. A battery of neuroimaging tasks are …
[HTML][HTML] Reward, motivation and brain imaging in human healthy participants–A narrative review
AM Weinstein - Frontiers in Behavioral Neuroscience, 2023 - frontiersin.org
Over the past twenty years there has been an increasing number of brain imaging studies on
the mechanisms underlying reward motivation in humans. This narrative review describes …
the mechanisms underlying reward motivation in humans. This narrative review describes …
[HTML][HTML] Reliability and stability challenges in ABCD task fMRI data
JT Kennedy, MP Harms, O Korucuoglu, SV Astafiev… - Neuroimage, 2022 - Elsevier
Trait stability of measures is an essential requirement for individual differences research.
Functional MRI has been increasingly used in studies that rely on the assumption of trait …
Functional MRI has been increasingly used in studies that rely on the assumption of trait …
[HTML][HTML] The neural substrate of reward anticipation in health: a meta-analysis of fMRI findings in the monetary incentive delay task
The monetary incentive delay task breaks down reward processing into discrete stages for
fMRI analysis. Here we look at anticipation of monetary gain and loss contrasted with neutral …
fMRI analysis. Here we look at anticipation of monetary gain and loss contrasted with neutral …
[HTML][HTML] Brain activations associated with anticipation and delivery of monetary reward: A systematic review and meta-analysis of fMRI studies
Background While multiple studies have examined the brain functional correlates of reward,
meta-analyses have either focused on studies using the monetary incentive delay (MID) …
meta-analyses have either focused on studies using the monetary incentive delay (MID) …
[PDF][PDF] Distinct reward processing by subregions of the nucleus accumbens
G Chen, S Lai, G Bao, J Ke, X Meng, S Lu, X Wu, H Xu… - Cell Reports, 2023 - cell.com
The nucleus accumbens (NAc) plays an important role in motivation and reward processing.
Recent studies suggest that different NAc subnuclei differentially contribute to reward …
Recent studies suggest that different NAc subnuclei differentially contribute to reward …
[HTML][HTML] When the brain comes into play: Neurofunctional correlates of emotions and reward in game-based learning
Accumulating evidence identifies emotions as drivers of effective learning. In parallel, game-
based learning was found to emotionally engage learners, allegedly harnessing the …
based learning was found to emotionally engage learners, allegedly harnessing the …