Gait analysis using animal models of peripheral nerve and spinal cord injuries

G Isvoranu, E Manole, M Neagu - Biomedicines, 2021 - mdpi.com
The present review discusses recent data regarding rodent models of spinal cord and
peripheral nerve injuries in terms of gait analysis using the CatWalk system (CW), an …

[HTML][HTML] Targeted up-regulation of Drp1 in dorsal horn attenuates neuropathic pain hypersensitivity by increasing mitochondrial fission

KL Zhang, SJ Li, XY Pu, FF Wu, H Liu, RQ Wang… - Redox Biology, 2022 - Elsevier
Mitochondria play an essential role in pathophysiology of both inflammatory and
neuropathic pain (NP), but the mechanisms are not yet clear. Dynamin-related protein 1 …

Intraarticular monomethyl fumarate as a perspective therapy for osteoarthritis by macrophage polarization

DM de Souza, KF Malange, CM Nishijima… - …, 2024 - Springer
Background Osteoarthritis (OA) is a chronic disease that may lead to joint structure
degeneration, cartilage destruction, osteophyte formation, subchondral bone disruption, and …

[HTML][HTML] Spinal cord stimulation paradigms and alleviation of neuropathic pain behavior in experimental painful diabetic polyneuropathy

TJ de Geus, G Franken, EAJ Joosten - Neuromodulation: Technology at the …, 2024 - Elsevier
Objectives Spinal cord stimulation (SCS) is an alternative treatment option for painful
diabetic polyneuropathy (PDPN). Differential target multiplexed (DTM)-SCS is proposed to …

Peripheral BDNF Regulates Somatosensory–Sympathetic Coupling in Brachial Plexus Avulsion-Induced Neuropathic Pain

H Xian, H Guo, YY Liu, JL Zhang, WC Hu, MJ Yu… - Neuroscience …, 2023 - Springer
Brachial plexus avulsion (BPA) is a combined injury involving the central and peripheral
nervous systems. Patients with BPA often experience severe neuropathic pain (NP) in the …

The effects of graft source and orientation on outcomes after ablation of a branched peripheral nerve

JAE Allgood, KCS Roballo, BB Sparks… - Frontiers in Cellular …, 2022 - frontiersin.org
Segmental peripheral nerve injuries (PNI) are the most common cause of enduring nervous
system dysfunction. The peripheral nervous system (PNS) has an extensive and highly …

Nasal administration of polysaccharides-based nanocarrier combining hemoglobin and diferuloylmethane for managing diabetic kidney disease

AEY Chuang, YL Chen, HJ Chiu, HT Nguyen… - International Journal of …, 2024 - Elsevier
The management of diabetic kidney disease (DKD) faces challenges stemming from
intricate pathologies and suboptimal biodistributions during drug delivery. Although clinically …

The Implications of Brain-Derived Neurotrophic Factor in the Biological Activities of Platelet-Rich Plasma

KF Malange, DM de Souza, JBP Lemes, CC Fagundes… - Inflammation, 2024 - Springer
Platelet-rich plasma (PRP) is a biological blood-derived therapeutic obtained from whole
blood that contains higher levels of platelets. PRP has been primarily used to mitigate joint …

Arginine vasopressin induces analgesic effects and inhibits pyramidal cells in the anterior cingulate cortex in spared nerve injured mice

HX Si, XD Liu, CY Sun, SM Yang… - American Journal …, 2024 - journals.physiology.org
Neuropathic pain (NP) is a severe disease caused by a primary disease or lesion affecting
the somatosensory nervous system. It is reported that NP is related to the increased activity …

Anti-hyperalgesic effects of photobiomodulation therapy (904 nm) on streptozotocin-induced diabetic neuropathy imply MAPK pathway and calcium dynamics …

WF Vieira, KF Malange, SF de Magalhães… - Scientific Reports, 2022 - nature.com
Several recent studies have established the efficacy of photobiomodulation therapy (PBMT)
in painful clinical conditions. Diabetic neuropathy (DN) can be related to activating mitogen …