Obesity: a chronic relapsing progressive disease process. A position statement of the World Obesity Federation

GA Bray, KK Kim, JPH Wilding… - Obesity …, 2017 - Wiley Online Library
This paper considers the argument for obesity as a chronic relapsing disease process.
Obesity is viewed from an epidemiological model, with an agent affecting the host and …

Hypothalamic circuits regulating appetite and energy homeostasis: pathways to obesity

K Timper, JC Brüning - Disease models & mechanisms, 2017 - journals.biologists.com
The 'obesity epidemic'represents a major global socioeconomic burden that urgently calls
for a better understanding of the underlying causes of increased weight gain and its …

A new animal diet based on human Western diet is a robust diet-induced obesity model: comparison to high-fat and cafeteria diets in term of metabolic and gut …

RC Bortolin, AR Vargas, J Gasparotto… - International Journal of …, 2018 - nature.com
Methods: Wistar rats were fed four different diets (WD, CAF, HFD and a low-fat diet) for 18
weeks. Metabolic parameters and gut microbiota changes were then characterized. Results …

Biochemical and nutritional overview of diet-induced metabolic syndrome models in rats: what is the best choice?

E Rodríguez-Correa, I González-Pérez… - Nutrition & …, 2020 - nature.com
Metabolic syndrome (MS) is a condition that includes obesity, insulin resistance,
dyslipidemias among other, abnormalities that favors type 2 Diabetes Mellitus (T2DM) and …

Microbiota‐gut‐brain axis as a regulator of reward processes

R García‐Cabrerizo, C Carbia… - Journal of …, 2021 - Wiley Online Library
Our gut harbours trillions of microorganisms essential for the maintenance of homeostasis
and host physiology in health and disease. In the last decade, there has been a growing …

Hyper‐palatable foods: development of a quantitative definition and application to the US food system database

TL Fazzino, K Rohde, DK Sullivan - Obesity, 2019 - Wiley Online Library
Objective Extensive research has focused on hyper‐palatable foods (HPF); however, HPF
are defined using descriptive terms (eg, fast foods, sweets), which are not standardized and …

Metabolic hormone action in the VTA: Reward-directed behavior and mechanistic insights

CE Geisler, MR Hayes - Physiology & behavior, 2023 - Elsevier
Dysfunctional signaling in midbrain reward circuits perpetuates diseases characterized by
compulsive overconsumption of rewarding substances such as substance abuse, binge …

Disordered eating behaviors and food addiction among nutrition major college students

Z Yu, M Tan - Nutrients, 2016 - mdpi.com
Evidence of whether nutrition students are free from food-related issues or at higher risk for
eating disorders is inconsistent. This study aimed to assess disordered eating behaviors and …

Ghrelin and food reward

O Al Massadi, R Nogueiras, C Dieguez, JA Girault - Neuropharmacology, 2019 - Elsevier
Food intake is tightly regulated by homeostatic and reward mechanisms and the adequate
function of both is necessary for the proper maintenance of energy balance. Ghrelin impacts …

Effect of the holiday season on weight gain: a narrative review

RG Díaz-Zavala, MF Castro-Cantú… - Journal of …, 2017 - Wiley Online Library
Several studies suggest that the holiday season, starting from the last week of November to
the first or second week of January, could be critical to gaining weight. This study aims to …