Rational design of immunomodulatory hydrogels for chronic wound healing
With all the advances in tissue engineering for construction of fully functional skin tissue,
complete regeneration of chronic wounds is still challenging. Since immune reaction to the …
complete regeneration of chronic wounds is still challenging. Since immune reaction to the …
mRNA vaccine era—mechanisms, drug platform and clinical prospection
S Xu, K Yang, R Li, L Zhang - International journal of molecular sciences, 2020 - mdpi.com
Messenger ribonucleic acid (mRNA)-based drugs, notably mRNA vaccines, have been
widely proven as a promising treatment strategy in immune therapeutics. The extraordinary …
widely proven as a promising treatment strategy in immune therapeutics. The extraordinary …
A microneedle vaccine printer for thermostable COVID-19 mRNA vaccines
Decentralized manufacture of thermostable mRNA vaccines in a microneedle patch (MNP)
format could enhance vaccine access in low-resource communities by eliminating the need …
format could enhance vaccine access in low-resource communities by eliminating the need …
Opportunities and challenges in the delivery of mRNA-based vaccines
In the past few years, there has been increasing focus on the use of messenger RNA
(mRNA) as a new therapeutic modality. Current clinical efforts encompassing mRNA-based …
(mRNA) as a new therapeutic modality. Current clinical efforts encompassing mRNA-based …
Current trends in polymer microneedle for transdermal drug delivery
KAS Al-Japairai, S Mahmood, SH Almurisi… - International journal of …, 2020 - Elsevier
Transdermal drug delivery using microneedles is increasingly gaining interest due to the
issues associated with oral drug delivery routes. Gastrointestinal route exposes the drug to …
issues associated with oral drug delivery routes. Gastrointestinal route exposes the drug to …
Microneedles for painless transdermal immunotherapeutic applications
Immunotherapy has recently garnered plenty of attention to improve the clinical outcomes in
the treatment of various diseases. However, owing to the dynamic nature of the immune …
the treatment of various diseases. However, owing to the dynamic nature of the immune …
Strategies to reduce the risks of mRNA drug and vaccine toxicity
D Bitounis, E Jacquinet, MA Rogers… - Nature Reviews Drug …, 2024 - nature.com
Abstract mRNA formulated with lipid nanoparticles is a transformative technology that has
enabled the rapid development and administration of billions of coronavirus disease 2019 …
enabled the rapid development and administration of billions of coronavirus disease 2019 …
[HTML][HTML] Recent approaches for enhancing the performance of dissolving microneedles in drug delivery applications
Dissolving microneedles (dMNs) are promising versatile drug delivery systems for the
transdermal delivery of numerous drugs, enabling their use in a wide range of biomedical …
transdermal delivery of numerous drugs, enabling their use in a wide range of biomedical …
Chemical strategies to boost cancer vaccines
WH Li, YM Li - Chemical reviews, 2020 - ACS Publications
Personalized cancer vaccines (PCVs) are reinvigorating vaccine strategies in cancer
immunotherapy. In contrast to adoptive T-cell therapy and checkpoint blockade, the PCV …
immunotherapy. In contrast to adoptive T-cell therapy and checkpoint blockade, the PCV …
From COVID-19 to cancer mRNA vaccines: moving from bench to clinic in the vaccine landscape
Recently, mRNA vaccines have become a significant type of therapeutic and have created
new fields in the biopharmaceutical industry. mRNA vaccines are promising next-generation …
new fields in the biopharmaceutical industry. mRNA vaccines are promising next-generation …