Enzymology of NAD+ homeostasis in man

G Magni, A Amici, M Emanuelli, G Orsomando… - Cellular and Molecular …, 2004 - Springer
This review describes the enzymes involved in human pyridine nucleotide metabolism
starting with a detailed consideration of their major kinetic, molecular and structural …

Regulatory SNPs: altered transcription factor binding sites implicated in complex traits and diseases

AO Degtyareva, EV Antontseva… - International journal of …, 2021 - mdpi.com
The vast majority of the genetic variants (mainly SNPs) associated with various human traits
and diseases map to a noncoding part of the genome and are enriched in its regulatory …

Understanding user privacy in Internet of Things environments

H Lee, A Kobsa - 2016 IEEE 3rd World Forum on Internet of …, 2016 - ieeexplore.ieee.org
During the past decade, user privacy has become an important issue in networked
computing environments. For instance, mobile applications and devices are increasingly …

Genetics of alcohol and tobacco use in humans

RF Tyndale - Annals of medicine, 2003 - Taylor & Francis
The field of genetics holds great promise for furthering our understanding of the etiology of
drug dependence and for identifying novel targets for treatment. Genetic studies utilizing …

rSNPBase: a database for curated regulatory SNPs

L Guo, Y Du, S Chang, K Zhang… - Nucleic acids research, 2014 - academic.oup.com
In recent years, human regulatory SNPs (rSNPs) have been widely studied. Here, we
present database rSNPBase, freely available at http://rsnp. psych. ac. cn/, to provide curated …

Single nucleotide polymorphism in transcriptional regulatory regions and expression of environmentally responsive genes

X Wang, DJ Tomso, X Liu, DA Bell - Toxicology and applied pharmacology, 2005 - Elsevier
Single nucleotide polymorphisms (SNPs) in the human genome are DNA sequence
variations that can alter an individual's response to environmental exposure. SNPs in gene …

Genome-wide scan of bipolar disorder in 65 pedigrees: supportive evidence for linkage at 8q24, 18q22, 4q32, 2p12, and 13q12

MG McInnis, TH Lan, VL Willour, FJ McMahon… - Molecular …, 2003 - nature.com
The purpose of this study was to assess 65 pedigrees ascertained through a Bipolar I (BPI)
proband for evidence of linkage, using nonparametric methods in a genome-wide scan and …

Polymorphisms in genes involved in neurotransmission in relation to smoking

T Arinami, H Ishiguro, ES Onaivi - European journal of pharmacology, 2000 - Elsevier
Smoking behavior is influenced by both genetic and environmental factors. The genetic
contribution to smoking behavior is at least as great as its contribution to alcoholism. Much …

How to Use SNP_TATA_Comparator to Find a Significant Change in Gene Expression Caused by the Regulatory SNP of This Gene's Promoter via a Change in …

M Ponomarenko, D Rasskazov… - BioMed Research …, 2015 - Wiley Online Library
The use of biomedical SNP markers of diseases can improve effectiveness of treatment.
Genotyping of patients with subsequent searching for SNPs more frequent than in norm is …

Серотониновая система в модуляции депрессивного и аддиктивного поведения

НА Бохан, СА Иванова, ЛА Левчук - 2013 - elibrary.ru
В предлагаемой вниманию читательской аудитории монографии освещены
современные гипотезы участия серотониновой системы в формировании …