The fungal kingdom comprises some of the most devastating plant pathogens. Sequencing
the genomes of fungal pathogens has shown a remarkable variability in genome size and …

Evolution of RNA viruses occurs through disequilibria of collections of closely related mutant
spectra or mutant clouds termed viral quasispecies. Here we review the origin of the …

Eukaryotic cytosine methylation represses transcription but also occurs in the bodies of
active genes, and the extent of methylation biology conservation is unclear. We quantified …

Sexual reproduction is a fundamental aspect of life. It is defined by the occurrence of meiosis
and the fusion of two gametes of different sexes or mating types. Sex-determination …

Genes in prokaryotic genomes are often arranged into clusters and co-transcribed into
polycistronic RNAs. Isolated examples of polycistronic RNAs were also reported in some …

Within the life cycle of a living organism, another life cycle exists for the selfish genome
inhabitants, which are called transposable elements (TEs). These mobile sequences invade …

The genomes of many animals, plants and fungi are tagged by methylation of DNA cytosine.
To understand the biological significance of this epigenetic mark it is essential to know …

▪ Abstract Large-genome eukaryotes use heritable cytosine methylation to silence
promoters, especially those associated with transposons and imprinted genes. Cytosine …

Much remains unknown regarding speciation. Host–pathogen interactions are a major
driving force for diversification, but the genomic basis for speciation and host shifting …

Metarhizium spp. are being used as environmentally friendly alternatives to chemical
insecticides, as model systems for studying insect-fungus interactions, and as a resource of …