Current research and clinical trends in rosacea pathogenesis

XM Hu, ZX Li, DY Zhang, YC Yang, SY Zheng, Q Zhang… - Heliyon, 2022 - cell.com
Background Rosacea is a common and complex chronic inflammatory skin disorder, the
pathophysiology and etiology of which remain unclear. Recently, significant new insights …

Immune homeostasis modulation by hydrogel-guided delivery systems: a tool for accelerated bone regeneration

B Mi, Y Xiong, K Zha, F Cao, W Zhou… - Biomaterials …, 2023 - pubs.rsc.org
Immune homeostasis is delicately mediated by the dynamic balance between effector
immune cells and regulatory immune cells. Local deviations from immune homeostasis in …

Quality of life measurement in rosacea. Position statement of the European academy of dermatology and Venereology task forces on quality of life and patient oriented …

PV Chernyshov, AY Finlay… - Journal of the …, 2023 - Wiley Online Library
Abstract The European Academy of Dermatology and Venereology (EADV) Task Forces
(TFs) on Quality of Life (QoL) and Patient‐Oriented Outcomes and Acne, Rosacea and …

[HTML][HTML] Dietary supplementation of n-3 PUFAs ameliorates LL37-induced rosacea-like skin inflammation via inhibition of TLR2/MyD88/NF-κB pathway

S Shen, G Yan, Y Cao, Q Zeng, J Zhao, X Wang… - Biomedicine & …, 2023 - Elsevier
Rosacea is a facial chronic inflammatory skin disease with dysfunction of immune and
neurovascular system and treatments for rosacea are challenging. N-3 polyunsaturated fatty …

Integrated omics reveal the molecular characterization and pathogenic mechanism of rosacea

Y Zhang, Y Huang, B Wang, W Shi, X Hu… - Journal of Investigative …, 2024 - Elsevier
Recent efforts have described the transcriptomic landscape of rosacea. However, little is
known about its proteomic characteristics. In this study, the proteome and phosphoproteome …

Exploring the pathogenesis and mechanism-targeted treatments of rosacea: previous understanding and updates

C Chen, P Wang, L Zhang, X Liu, H Zhang, Y Cao… - Biomedicines, 2023 - mdpi.com
Rosacea is a chronic inflammatory skin disease characterized by recurrent erythema,
flushing, telangiectasia, papules, pustules, and phymatous changes in the central area of …

Biomarkers in rosacea: A systematic review

RSQ Geng, AN Bourkas, RG Sibbald… - Journal of the …, 2024 - Wiley Online Library
Rosacea is a chronic and psychologically ladened disease affecting 1%–3% of people
worldwide. The identification and validation of biomarkers in rosacea patients has the …

[HTML][HTML] Celastrol inhibits LL37-induced rosacea by inhibiting Ca2+/CaMKII-mTOR-NF-κB activation

Q Zeng, J Yang, G Yan, L Zhang, P Wang… - Biomedicine & …, 2022 - Elsevier
Rosacea is a common chronic facial inflammatory disease that affects millions of people
worldwide. Due to the unclear etiology of rosacea, effective treatments are limited. Celastrol …

Oroxylin A suppress LL-37 generated rosacea-like skin inflammation through the modulation of SIRT3-SOD2-NF-κB signaling pathway

C Feng, H Zhang, P Wang, L Zhang, X Liu… - International …, 2024 - Elsevier
Rosacea is a long-term inflammatory skin disease associated with the dysfunction of
vascular and immunological systems. Treatment options for rosacea are difficult to …

Pyroptosis‐related gene signature elicits immune response in rosacea

X Hu, S Zheng, R Mao, Q Zhang, X Wan… - Experimental …, 2024 - Wiley Online Library
Rosacea is a complex chronic inflammatory skin disorder with high morbidity. Pyroptosis is
known as a regulated inflammatory cell death. While its association with immune response …