The therapeutic potential of irisin to mitigate the risk of metabolic syndrome in postmenopausal women

RA Parkin, AJ Murray - Frontiers in Reproductive Health, 2024 - frontiersin.org
Oestradiol withdrawal at menopause predisposes women to metabolic syndrome, a cluster
of interrelated conditions including obesity, insulin resistance, dyslipidaemia and …

Irisin alleviated the reproductive endocrinal disorders of PCOS mice accompanied by changes in gut microbiota and metabolomic characteristics

M Yang, H Deng, S Zhou, D Lu, X Shen… - Frontiers in …, 2024 - frontiersin.org
Introduction Folliculogenesis and oligo/anovulation are common pathophysiological
characteristics in polycystic ovary syndrome (PCOS) patients, and it is also accompanied by …

Effects of Melatonin Supplementation on Lipid Metabolism and Body Fat Accumulation in Ovariectomized Rats

LW Hsu, YW Chien - Nutrients, 2023 - mdpi.com
Postmenopausal obesity is a rising problem. Melatonin (Mel) is a hormone secreted by the
pineal gland that regulates the circadian rhythms and improves obesity. In this experiment …

Swimming alleviates myocardial fibrosis of type II diabetic rats through activating miR-34a-mediated SIRT1/PGC-1α/FNDC5 signal pathway

Y Guo, F Zhou, J Fan, T Wu, S Jia, J Li, N Chen - Plos one, 2024 - journals.plos.org
Myocardial fibrosis can trigger heart failure in diabetic cardiomyopathy (DCM), and irisin, an
exercise-induced myokine, may have a beneficial effect on cardiac function. However, the …

Association of Serum Irisin Levels with Body Composition, Metabolic Profile, Leptin, and Adiponectin Levels in Lean and Obese Children

K Esin, S Batirel, G Ülfer, P Yigit, N Sanlier - Medicina, 2023 - mdpi.com
Background and Objectives: Irisin is an adipo-myokine with potential metabolic effects in the
body, and its association with childhood obesity is still controversial. This study aimed to …

(-)-epicatechin treatment did not modify the thermogenic pathway in the gastrocnemius muscle of male rat offspring obeses by programming

ME Tejeda, S De los Santos… - … Origins of Health and …, 2024 - cambridge.org
The aim of this study was to analyse the expression of genes related to the regulation of
energy metabolism in skeletal muscle tissue by comparing male offspring in two age groups …

Identification of leptolin as a novel anti-obesity adipokine

J Liu, B Wang, Z Su, X Han, M He, Y Zhao, Y Hou, D Li… - bioRxiv, 2024 - biorxiv.org
Adipokines are key factors in regulating energy homeostasis. We identified a novel
adipokine; we named it Leptolin. In humans, leptolin levels in white adipose tissue were …

High-intensity interval training increases thermogenesis and metabolism through changes in regulatory proteins

AH Jafari, M Fasihiyan, M Taheri… - Journal of Exercise & …, 2023 - jeoct.com
The present study aimed to investigate the effect of 4 weeks of high-intensity interval training
on the amounts of metabolic proteins like Sarcolipine, PGC1α and FNDC5 in SOL and EDL …

[PDF][PDF] ВЛИЯНИЕ ФОНОВОЙ ЛИМФОПЕНИИ НА РЕАКТИВНОСТЬ ПОКАЗАТЕЛЕЙ НЕСПЕЦИФИЧЕСКОГО ИММУНИТЕТА В ОТВЕТ НА ОБЩЕЕ ХОЛОДОВОЕ …

ВП Патракеева, ЕВ Контиевская - mes.fmba.press
Compliance with ethical standards: the study was conducted with the written consent of all
participants and in accordance with the principles of the Declaration of Helsinki (1975, rev …

[PDF][PDF] THE IMPACT OF BACKGROUND LYMPHOPENIA ON THE REACTIVITY OF NONSPECIFIC IMMUNITY IN RESPONSE TO TOTAL BODY COLD EXPOSURE

VP Patrakeeva, EV Kontievskaya - mes.fmba.press
METHODS Hematological and immunological parameters were measured before and
immediately after total body cold exposure in two groups of volunteers (203 participants in …