Chronic wasting disease: a cervid prion infection looming to spillover
A Otero, CD Velásquez, J Aiken, D McKenzie - Veterinary Research, 2021 - Springer
The spread of chronic wasting disease (CWD) during the last six decades has resulted in
cervid populations of North America where CWD has become enzootic. This insidious …
cervid populations of North America where CWD has become enzootic. This insidious …
Cervid prion protein polymorphisms: role in chronic wasting disease pathogenesis
MI Arifin, S Hannaoui, SC Chang, S Thapa… - International journal of …, 2021 - mdpi.com
Chronic wasting disease (CWD) is a prion disease found in both free-ranging and farmed
cervids. Susceptibility of these animals to CWD is governed by various exogenous and …
cervids. Susceptibility of these animals to CWD is governed by various exogenous and …
Shedding and stability of CWD prion seeding activity in cervid feces
JM Tennant, M Li, DM Henderson, ML Tyer… - PloS one, 2020 - journals.plos.org
CWD is an emergent prion disease that now affects cervid species on three continents. CWD
is efficiently spread in wild and captive populations, likely through both direct animal contact …
is efficiently spread in wild and captive populations, likely through both direct animal contact …
Detection of chronic wasting disease in mule and white-tailed deer by RT-QuIC analysis of outer ear
NC Ferreira, JM Charco, J Plagenz, CD Orru… - Scientific reports, 2021 - nature.com
Efforts to contain the spread of chronic wasting disease (CWD), a fatal, contagious prion
disease of cervids, would be aided by the availability of additional diagnostic tools. RT-QuIC …
disease of cervids, would be aided by the availability of additional diagnostic tools. RT-QuIC …
Early and non-invasive detection of chronic wasting disease prions in elk feces by real-time quaking induced conversion
YC Cheng, S Hannaoui, TR John, S Dudas, S Czub… - PloS one, 2016 - journals.plos.org
Chronic wasting disease (CWD) is a fatal prion disease of wild and captive cervids in North
America. Prions are infectious agents composed of a misfolded version of a host-encoded …
America. Prions are infectious agents composed of a misfolded version of a host-encoded …
Spatiotemporal epizootiology of chronic wasting disease in Wisconsin deer
MD Samuel - Ecosphere, 2023 - Wiley Online Library
Chronic wasting disease (CWD) is a fatal neurological disease of cervids caused by a
misfolded protein with no vaccines or other cures to prevent infection and death. In the past …
misfolded protein with no vaccines or other cures to prevent infection and death. In the past …
Pathways of prion spread during early chronic wasting disease in deer
CE Hoover, KA Davenport, DM Henderson… - Journal of …, 2017 - Am Soc Microbiol
Among prion infections, two scenarios of prion spread are generally observed:(i) early
lymphoid tissue replication or (ii) direct neuroinvasion without substantial antecedent …
lymphoid tissue replication or (ii) direct neuroinvasion without substantial antecedent …
Very low oral exposure to prions of brain or saliva origin can transmit chronic wasting disease
ND Denkers, CE Hoover, KA Davenport… - PloS one, 2020 - journals.plos.org
The minimum infectious dose required to induce CWD infection in cervids remains unknown,
as does whether peripherally shed prions and/or multiple low dose exposures are important …
as does whether peripherally shed prions and/or multiple low dose exposures are important …
Evaluation of real-time quaking-induced conversion, ELISA, and immunohistochemistry for chronic wasting disease diagnosis
CL Holz, JR Darish, K Straka, N Grosjean… - Frontiers in Veterinary …, 2022 - frontiersin.org
Chronic wasting disease (CWD) is a transmissible prion disorder, primarily affecting free-
ranging and captive cervids in North America (United States and Canada), South Korea, and …
ranging and captive cervids in North America (United States and Canada), South Korea, and …
Chronic wasting disease: an evolving prion disease of cervids
SL Benestad, GC Telling - Handbook of clinical neurology, 2018 - Elsevier
Chronic wasting disease (CWD) is a relatively new and burgeoning prion epidemic of deer,
elk, reindeer, and moose, which are members of the cervid family. While the disease was …
elk, reindeer, and moose, which are members of the cervid family. While the disease was …