The emergence of COVID-19 associated mucormycosis: a review of cases from 18 countries

M Hoenigl, D Seidel, A Carvalho… - The Lancet …, 2022 - thelancet.com
Reports of COVID-19-associated mucormycosis have been increasing in frequency since
early 2021, particularly among patients with uncontrolled diabetes. Patients with diabetes …

Epidemiology and pathophysiology of COVID-19-associated mucormycosis: India versus the rest of the world

V Muthu, SM Rudramurthy, A Chakrabarti, R Agarwal - Mycopathologia, 2021 - Springer
Abstract The coronavirus disease 2019 (COVID-19) pandemic has led to a concerning
resurgence of mucormycosis. More than 47,000 cases of mucormycosis were reported in …

Mucormycosis in 2023: An update on pathogenesis and management

A Alqarihi, DP Kontoyiannis, AS Ibrahim - Frontiers in Cellular and …, 2023 - frontiersin.org
Mucormycosis (MCR) is an emerging and frequently lethal fungal infection caused by the
Mucorales family, with Rhizopus, Mucor, and Lichtheimia, accounting for> 90% of all cases …

Mucorales species and macrophages

FE Nicolás, L Murcia, E Navarro, MI Navarro-Mendoza… - Journal of Fungi, 2020 - mdpi.com
Mucormycosis is an emerging fungal infection caused by Mucorales with an unacceptable
high mortality rate. Mucorales is a complex fungal group, including eleven different genera …

Mucorales and Mucormycosis: Recent Insights and Future Prospects

G Tahiri, C Lax, JT Cánovas-Márquez, P Carrillo-Marín… - Journal of Fungi, 2023 - mdpi.com
The classification of Mucorales encompasses a collection of basal fungi that have
traditionally demonstrated an aversion to modern genetic manipulation techniques. This …

The RNAi universe in fungi: a varied landscape of small RNAs and biological functions

S Torres-Martínez… - Annual Review of …, 2017 - annualreviews.org
RNA interference (RNAi) is a conserved eukaryotic mechanism that uses small RNA
molecules to suppress gene expression through sequence-specific messenger RNA …

Genes, pathways, and mechanisms involved in the virulence of mucorales

C Lax, C Pérez-Arques, MI Navarro-Mendoza… - Genes, 2020 - mdpi.com
The order Mucorales is a group of ancient fungi with limited tools for gene manipulation. The
main consequence of this manipulation unwillingness is the limited knowledge about its …

Broad antifungal resistance mediated by RNAi-dependent epimutation in the basal human fungal pathogen Mucor circinelloides

Z Chang, RB Billmyre, SC Lee, J Heitman - PLoS Genetics, 2019 - journals.plos.org
Mucormycosis—an emergent, deadly fungal infection—is difficult to treat, in part because the
causative species demonstrate broad clinical antifungal resistance. However, the …

Stable and reproducible homologous recombination enables CRISPR-based engineering in the fungus Rhizopus microsporus

C Lax, MI Navarro-Mendoza, C Pérez-Arques… - Cell Reports …, 2021 - cell.com
Mucormycosis is a lethal and emerging disease that has lacked a genetic model fulfilling
both high virulence and the possibility of performing stable and reproducible gene …

Secretion of the siderophore rhizoferrin is regulated by the cAMP-PKA pathway and is involved in the virulence of Mucor lusitanicus

V Alejandre-Castañeda, JA Patiño-Medina… - Scientific Reports, 2022 - nature.com
Mucormycosis is a fungal infection caused by Mucorales, with a high mortality rate.
However, only a few virulence factors have been described in these organisms. This study …