Calcium, phosphate, and magnesium are multivalent cations that are important for many
biologic and cellular functions. The kidneys play a central role in the homeostasis of these …

Phosphate is one of the most abundant minerals in the body, and its serum levels are
regulated by a complex set of processes occurring in the intestine, skeleton, and kidneys …

Whether kidney proximal tubule harbors a scattered population of epithelial stem cells is a
major unsolved question. Lineage-tracing studies, histologic characterization, and ex vivo …

This brief review focuses on calcium balance and homeostasis and their relationship to
dietary calcium intake and calcium supplementation in healthy subjects and patients with …

In addition to its role as a metabolic waste product, uric acid has been proposed to be an
important molecule with multiple functions in human physiologic and pathophysiologic …

The human kidneys produce approximately 160–170 L of ultrafiltrate per day. The proximal
tubule contributes to fluid, electrolyte, and nutrient homeostasis by reabsorbing …

-El libro ayuda a conocer las funciones normales del cuerpo, esenciales para una práctica
veterinaria satisfactoria, y los mecanismos de las enfermedades.-Aborda esta amplia …

OBJECTIVE Klotho is an antiaging hormone present in the kidney that extends the lifespan,
regulates kidney function, and modulates cellular responses to oxidative stress. We …

The classical paradigm of G protein-coupled receptor (GPCR) signaling via G proteins is
grounded in a view that downstream responses are relatively transient and confined to the …

Tissue homeostasis and regeneration are fueled by resident stem cells that have the
capacity to self-renew, and to generate all the differentiated cell types that characterize a …