Spinal cord injury (SCI) often leads to serious motor and sensory dysfunction of the limbs
below the injured segment. SCI not only results in physical and psychological harm to …

Ischemic disorders, such as myocardial infarction, stroke, and peripheral vascular disease,
are the most common causes of debilitating disease and death in westernized cultures. The …

Background Spinal cord injury (SCI) can lead to severe motor and sensory dysfunction with
high disability and mortality. In recent years, mesenchymal stem cell (MSC)-secreted nano …

Clinical trials using adult stem cells to regenerate damaged heart tissue continue to this
day,, despite ongoing questions of efficacy and a lack of mechanistic understanding of the …

Increasing evidence has suggested that paracrine mechanisms might be involved in the
underlying mechanism of mesenchymal stem cells (MSCs) transplantation, and exosomes …

Circulation. 2017; 136: 680–686. DOI: 10.1161/CIRCULATIONAHA. 117.029343 August 15,
2017 681 proliferation. 5 It remains unclear whether this regenerative window exists in large …

Spinal cord injury (SCI) can cause severe irreversible motor dysfunction and even death.
Neural stem cell (NSC) transplantation can promote functional recovery after acute SCI in …

A large number of clinical trials have shown stem cell therapy to be a promising therapeutic
approach for the treatment of cardiovascular diseases. Since the first transplantation into …

Current therapies for heart failure after myocardial infarction are limited and non-curative.
Although regenerative approaches are receiving significant attention, clinical efforts that …

The most common form of heart failure occurs with normal systolic function and often
involves cardiac hypertrophy in the elderly. To clarify the biological mechanisms that drive …