NRF2 (Nuclear factor E2 p45‐related factor 2) is a stress responsive transcription factor
lending cells resilience against oxidative, xenobiotic, and also nutrient or proteotoxic insults …

Macroautophagy/autophagy is an evolutionally conserved catabolic process in which
cytosolic contents, such as aggregated proteins, dysfunctional organelle, or invading …

Background Nutrient acquisition and metabolism pathways are altered in cancer cells to
meet bioenergetic and biosynthetic demands. A major regulator of cellular metabolism and …

Objective The AMP-activated protein kinase (AMPK) gets activated in response to energetic
stress such as contractions and plays a vital role in regulating various metabolic processes …

AMP-activated protein kinase (AMPK) is a master regulator of cellular energetics which
coordinates metabolism by phosphorylating a plethora of substrates throughout the cell. But …

The incidence and mortality of cancer are increasing, making it a leading cause of death
worldwide. Conventional treatments such as surgery, radiotherapy, and chemotherapy face …

The degradation of macromolecules and organelles by the process of autophagy is critical
for cellular homeostasis and is often compromised during aging and disease. Beclin1 and …

Triple negative breast cancer (TNBC) is the most aggressive type of breast cancers which
constitutes about 15% of all breast cancer cases and characterized by negative expression …

Metastatic colonization by circulating cancer cells is a highly inefficient process. To colonize
distant organs, disseminating cancer cells must overcome many obstacles in foreign …

The cellular mechanisms underlying axonal morphogenesis are essential to the formation of
functional neuronal networks. We previously identified the autism-linked kinase NUAK1 as a …