Although nosocomial infections by Staphylococcus epidermidis have gained much attention,
this skin-colonizing bacterium has apparently evolved not to cause disease, but to maintain …

Bacterial lipoproteins are a set of membrane proteins with many different functions. Due to
this broad-ranging functionality, these proteins have a considerable significance in many …

Multidrug-resistant, Gram-negative infection is a major global determinant of morbidity,
mortality and cost of care. The advent of nanomedicine has enabled tailored engineering of …

Since the discovery in 1973 of the first of the bacterial lipoproteins (Lpp) in Escherichia coli,
Braun's lipoprotein, the ever-increasing number of publications indicates the importance of …

Bacterial lipoproteins are characterized by the presence of a conserved N‐terminal lipid‐
modified cysteine residue that allows the hydrophilic protein to anchor onto bacterial cell …

The Toll-interleukin-1 Receptor (TIR) domain-containing adaptor protein (TIRAP) represents
a key intracellular signalling molecule regulating diverse immune responses. Its capacity to …

Group B Streptococcus commonly colonises healthy adults without symptoms, yet under
certain circumstances displays the ability to invade host tissues, evade immune detection …

Long noncoding RNA s (lnc RNA s) can regulate target gene expression by acting in cis
(locally) or in trans (non‐locally). Here, we performed genome‐wide expression analysis of …

Rationale: Polymorphisms affecting Toll-like receptor (TLR)–mediated responses could
predispose to excessive inflammation during an infection and contribute to an increased risk …

Gram-positive bacterial lipoproteins are a functionally diverse and important class of
peripheral membrane proteins. Recent advances in molecular biology and the availability of …