Innovations in image-guided radiotherapy
D Verellen, MD Ridder, N Linthout, K Tournel… - Nature Reviews …, 2007 - nature.com
The limited ability to control for the location of a tumour compromises the accuracy with
which radiation can be delivered to tumour-bearing tissue. The resultant requirement for …
which radiation can be delivered to tumour-bearing tissue. The resultant requirement for …
Prostate alpha/beta revisited–an analysis of clinical results from 14 168 patients
A Dasu, I Toma-Dasu - Acta Oncologica, 2012 - Taylor & Francis
Purpose. To determine the dose response parameters and the fractionation sensitivity of
prostate tumours from clinical results of patients treated with external beam radiotherapy …
prostate tumours from clinical results of patients treated with external beam radiotherapy …
Hypofractionated versus conventionally fractionated radiotherapy for patients with localised prostate cancer (HYPRO): final efficacy results from a randomised …
L Incrocci, RC Wortel, WG Alemayehu… - The Lancet …, 2016 - thelancet.com
Background Studies have reported a low α/β ratio for prostate cancer, suggesting that
hypofractionation could enhance the biological tumour dose without increasing …
hypofractionation could enhance the biological tumour dose without increasing …
Randomized trial of hypofractionated external-beam radiotherapy for prostate cancer
A Pollack, G Walker, EM Horwitz, R Price… - Journal of Clinical …, 2013 - ascopubs.org
Purpose To determine if escalated radiation dose using hypofractionation significantly
reduces biochemical and/or clinical disease failure (BCDF) in men treated primarily for …
reduces biochemical and/or clinical disease failure (BCDF) in men treated primarily for …
Long‐term survival after radical prostatectomy versus external‐beam radiotherapy for patients with high‐risk prostate cancer
SA Boorjian, RJ Karnes, R Viterbo, LJ Rangel… - Cancer, 2011 - Wiley Online Library
BACKGROUND: The long‐term survival of patients with high‐risk prostate cancer was
compared after radical prostatectomy (RRP) and after external beam radiation therapy …
compared after radical prostatectomy (RRP) and after external beam radiation therapy …
Hypofractionated intensity-modulated radiotherapy (70 Gy at 2.5 Gy per fraction) for localized prostate cancer: Cleveland Clinic experience
PA Kupelian, TR Willoughby, CA Reddy… - International Journal of …, 2007 - Elsevier
Purpose: To study the outcomes in patients treated for localized prostate cancer with 70 Gy
delivered at 2.5-Gy/fraction within 5 weeks. Methods and Materials: The study sample …
delivered at 2.5-Gy/fraction within 5 weeks. Methods and Materials: The study sample …
Dose–volume effects for normal tissues in external radiotherapy: pelvis
C Fiorino, R Valdagni, T Rancati… - Radiotherapy and …, 2009 - Elsevier
A great deal of quantitative information regarding the dose–volume relationships of pelvic
organs at risk has been collected and analysed over the last 10 years. The need to improve …
organs at risk has been collected and analysed over the last 10 years. The need to improve …
Hypofractionated versus conventionally fractionated radiotherapy for prostate carcinoma: final results of phase III randomized trial
EE Yeoh, RJ Botten, J Butters, AC Di Matteo… - International Journal of …, 2011 - Elsevier
PURPOSE: To evaluate the long-term efficacy and toxicity of a hypofractionated (55 Gy in 20
fractions within 4 weeks) vs. a conventionally fractionated (64 Gy in 32 fractions within 6.5 …
fractions within 4 weeks) vs. a conventionally fractionated (64 Gy in 32 fractions within 6.5 …
Updated results and patterns of failure in a randomized hypofractionation trial for high-risk prostate cancer
S Arcangeli, L Strigari, S Gomellini, B Saracino… - International Journal of …, 2012 - Elsevier
PURPOSE: To report long-term results and patterns of failure after conventional and
hypofractionated radiation therapy in high-risk prostate cancer. METHODS AND …
hypofractionated radiation therapy in high-risk prostate cancer. METHODS AND …
A (short) history of image-guided radiotherapy
D Verellen, M De Ridder, G Storme - Radiotherapy and Oncology, 2008 - Elsevier
Progress in radiotherapy is guided by the need to realize improved dose distributions, ie the
ability to reduce the treatment volume toward the target volume and still ensuring coverage …
ability to reduce the treatment volume toward the target volume and still ensuring coverage …