Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen that
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …

Pseudomonas aeruginosa is an opportunistic pathogen affecting immunocompromised
patients. It is known as the leading cause of morbidity and mortality in cystic fibrosis (CF) …

Pseudomonas aeruginosa causes severe and persistent infections in immune compromised
individuals and cystic fibrosis sufferers. The infection is hard to eradicate as P. aeruginosa …

Background is provided on biofilms, including their formation, tolerance mechanisms,
structure, and morphology within the context of chronic wounds. The features of biofilms in …

The substantial use of antibiotics in the clinic, combined with a dearth of new antibiotic
classes, has led to a gradual increase in the resistance of bacterial pathogens to these …

Cell-to-cell communication is a major process that allows bacteria to sense and coordinately
react to the fluctuating conditions of the surrounding environment. In several pathogens, this …

Biofilms are complex microbial associations anchored to abiotic or biotic surfaces,
embedded in extracellular matrix produced by the biofilms themselves where they interact …

Drug efflux pumps play a key role in drug resistance and also serve other functions in
bacteria. There has been a growing list of multidrug and drug-specific efflux pumps …

Lung infection is the main cause of morbidity and mortality in patients with cystic fibrosis and
is mainly dominated by Pseudomonas aeruginosa. The biofilm mode of growth makes …

Traditional treatment of infectious diseases is based on compounds that kill or inhibit growth
of bacteria. A major concern with this approach is the frequent development of resistance to …