Current treatment options for meningioma

C Apra, M Peyre, M Kalamarides - Expert review of …, 2018 - Taylor & Francis
Introduction: With an annual incidence of 5/100,000, meningioma is the most frequent
primary tumor of the central nervous system. Risk factors are radiotherapy and hormone …

Adjuvant radiotherapy for atypical and malignant meningiomas: a systematic review

G Kaur, ET Sayegh, A Larson, O Bloch… - Neuro …, 2014 - academic.oup.com
Atypical meningiomas (AMs) and malignant meningiomas (MMs) are tumors with a lower
incidence and poorer prognosis than benign meningiomas. The role of radiotherapy as an …

Adjuvant postoperative high-dose radiotherapy for atypical and malignant meningioma: a phase-II parallel non-randomized and observation study (EORTC 22042 …

DC Weber, C Ares, S Villa, SM Peerdeman… - Radiotherapy and …, 2018 - Elsevier
Purpose The therapeutic strategy for non-benign meningiomas is controversial. The
objective of this study was to prospectively investigate the impact of high dose radiation …

Descriptive epidemiology of World Health Organization grades II and III intracranial meningiomas in the United States

VR Kshettry, QT Ostrom, C Kruchko, O Al-Mefty… - Neuro …, 2015 - academic.oup.com
Abstract Background Because World Health Organization (WHO) grades II and III
meningiomas are relatively uncommon, there is limited literature on the descriptive …

WHO grade II and III meningiomas: a study of prognostic factors

A Durand, F Labrousse, A Jouvet, L Bauchet… - Journal of neuro …, 2009 - Springer
Meningiomas represent one of the largest subgroups of intracranial tumors. They are
generally benign, but may show a histological progression to malignancy. Grades II and III …

Anatomic location is a risk factor for atypical and malignant meningiomas

AJ Kane, ME Sughrue, MJ Rutkowski, G Shangari… - Cancer, 2011 - Wiley Online Library
Abstract BACKGROUND: Grade II and III meningiomas have higher rates of tumor
recurrence than grade I meningiomas after surgery and/or external irradiation. As the utility …

Increased expression of the immune modulatory molecule PD-L1 (CD274) in anaplastic meningioma

Z Du, M Abedalthagafi, AA Aizer, AR McHenry… - …, 2014 - pmc.ncbi.nlm.nih.gov
There are no effective medical treatments for WHO grade III (anaplastic) meningioma.
Patients with this high-grade malignancy have a median survival of less than two years …

The role of radiotherapy following gross-total resection of atypical meningiomas

RJ Komotar, JB Iorgulescu, DMS Raper… - Journal of …, 2012 - thejns.org
Object Atypical (WHO Grade II) meningiomas comprise a heterogeneous group of tumors,
with histopathology delineated under the guidance of the WHO and a spectrum of clinical …

Differentiating meningioma grade by imaging features on magnetic resonance imaging

AT Hale, L Wang, MK Strother… - Journal of Clinical …, 2018 - Elsevier
Atypical meningioma has an aggressive clinical course. Distinguishing atypical from benign
meningioma preoperatively could affect surgical planning and improve treatment outcomes …

Review of atypical and anaplastic meningiomas: classification, molecular biology, and management

TA Wilson, L Huang, D Ramanathan… - Frontiers in …, 2020 - frontiersin.org
Although the majority of meningiomas are slow-growing and benign, atypical and anaplastic
meningiomas behave aggressively with a penchant for recurrence. Standard of care …