Management of cancer metastasis has been associated with remarkable reduction in
progression of cancer cells and improving survival rate of patients. Since 90% of mortality …

Metastasis is one of the main contributors to the poor prognosis of hepatocellular carcinoma
(HCC). However, the underlying mechanism of HCC metastasis remains largely unknown …

In recent years, the discovery of 'tumour niche', a microenvironment that favours tumour
development has changed our perspective of cancer. This microenvironment generated by …

Ferroptosis is a type of regulated cell death characterized by lipid peroxidation and
subsequent damage to the plasma membrane. Here, we report a ferroptosis resistance …

Summary Cyclin-dependent kinase 4 (CDK4) and retinoblastoma protein (RB) are both
important cell-cycle regulators that function in different scenarios. Here, we report that FERM …

Background Folate and vitamin B-12 are essential micronutrients involved in the donation of
methyl groups in cellular metabolism. However, associations between intake of these …

Objectives: Lung adenocarcinoma (LUAD) accounts for a majority of cancer-related deaths
worldwide annually. The identification of prognostic biomarkers and prediction of prognosis …

Pre–B-cell leukemia homeobox (Pbx)-regulating protein-1 (Prep1) is a ubiquitous
homeoprotein involved in early development, genomic stability, insulin sensitivity, and …

Breast cancer is the most common cause of death in women worldwide. Approximately 5%–
10% of instances are attributed to mutations acquired from the parents. Therefore, it is highly …

Background Lung adenocarcinoma (LUAD) is a heterogeneous disease with poor survival
in the advanced stage and a high incidence rate in the world. Novel drug targets are …