The human microbiome is composed of a collection of dynamic microbial communities that
inhabit various anatomical locations in the body. Accordingly, the coevolution of the …

In the 20th century, the development, licensing and implementation of vaccines as part of
large, systematic immunization programs started to address health inequities that existed …

This report compiles and summarizes all published recommendations from CDC's Advisory
Committee on Immunization Practices (ACIP) for use of pneumococcal vaccines in adults …

The emergence of antimicrobial resistance (AMR) is a growing public health threat
worldwide and antibiotic consumption is being increasingly recognized as the main …

Streptococcus pneumoniae has a complex relationship with its obligate human host. On the
one hand, the pneumococci are highly adapted commensals, and their main reservoir on the …

Children could benefit both directly and indirectly from vaccination. In light of the safety and
immunogenicity results from recent adult COVID-19 vaccine clinical trials, children should …

Clin Microbiol Infect 2011; 17 (Suppl. 6): E1–E59 Abstract This document is an update of
Guidelines published in 2005 and now includes scientific publications through to May 2010 …

Evidenced-based guidelines for management of infants and children with community-
acquired pneumonia (CAP) were prepared by an expert panel comprising clinicians and …

Background The rate of bacterial meningitis declined by 55% in the United States in the
early 1990s, when the Haemophilus influenzae type b (Hib) conjugate vaccine for infants …

The pneumococcus is the classic Gram-positive extracellular pathogen. The medical burden
of diseases it causes is amongst the greatest in the world. Intense study for more than 100 …