[HTML][HTML] Antibiotic resistance: one health one world outlook

B Aslam, M Khurshid, MI Arshad… - Frontiers in cellular …, 2021 - frontiersin.org
Antibiotic resistance (ABR) is a growing public health concern worldwide, and it is now
regarded as a critical One Health issue. One Health's interconnected domains contribute to …

Defining and combating antibiotic resistance from One Health and Global Health perspectives

S Hernando-Amado, TM Coque, F Baquero… - Nature …, 2019 - nature.com
Several interconnected human, animal and environmental habitats can contribute to the
emergence, evolution and spread of antibiotic resistance, and the health of these contiguous …

[HTML][HTML] Towards monitoring of antimicrobial resistance in the environment: for what reasons, how to implement it, and what are the data needs?

J Bengtsson-Palme, A Abramova, TU Berendonk… - Environment …, 2023 - Elsevier
Antimicrobial resistance (AMR) is a global threat to human and animal health and well-
being. To understand AMR dynamics, it is important to monitor resistant bacteria and …

[HTML][HTML] Accelerating antibiotic discovery through artificial intelligence

MCR Melo, JRMA Maasch… - Communications …, 2021 - nature.com
By targeting invasive organisms, antibiotics insert themselves into the ancient struggle of the
host-pathogen evolutionary arms race. As pathogens evolve tactics for evading antibiotics …

Sequencing-based methods and resources to study antimicrobial resistance

M Boolchandani, AW D'Souza, G Dantas - Nature Reviews Genetics, 2019 - nature.com
Antimicrobial resistance extracts high morbidity, mortality and economic costs yearly by
rendering bacteria immune to antibiotics. Identifying and understanding antimicrobial …

[HTML][HTML] Strain-level characterization of broad host range mobile genetic elements transferring antibiotic resistance from the human microbiome

SC Forster, J Liu, N Kumar, EL Gulliver… - Nature …, 2022 - nature.com
Mobile genetic elements (MGEs) carrying antibiotic resistance genes (ARGs) disseminate
ARGs when they mobilise into new bacterial hosts. The nature of such horizontal gene …

[HTML][HTML] Using genomics to track global antimicrobial resistance

RS Hendriksen, V Bortolaia, H Tate, GH Tyson… - Frontiers in public …, 2019 - frontiersin.org
The recent advancements in rapid and affordable DNA sequencing technologies have
revolutionized diagnostic microbiology and microbial surveillance. The availability of …

MEGARes 2.0: a database for classification of antimicrobial drug, biocide and metal resistance determinants in metagenomic sequence data

E Doster, SM Lakin, CJ Dean, C Wolfe… - Nucleic acids …, 2020 - academic.oup.com
Antimicrobial resistance (AMR) is a threat to global public health and the identification of
genetic determinants of AMR is a critical component to epidemiological investigations. High …

Horizontal transfer of antibiotic resistance genes in the human gut microbiome

RS McInnes, GE McCallum, LE Lamberte… - Current opinion in …, 2020 - Elsevier
Highlights•The human gut microbiome harbours antibiotic resistance genes ('the
resistome').•Antibiotic resistance genes can spread in the gut microbiome through horizontal …

Innovative and rapid antimicrobial susceptibility testing systems

A van Belkum, CAD Burnham, JWA Rossen… - Nature Reviews …, 2020 - nature.com
Antimicrobial resistance (AMR) is a major threat to human health worldwide, and the rapid
detection and quantification of resistance, combined with antimicrobial stewardship, are key …