Chemoresistant metastatic relapse of minimal residual disease plays a significant role for
poor prognosis of cancer. Growing evidence supports a critical role of cancer stem cell …

Salivary gland cancer (SGC) is immensely heterogeneous, both in terms of its physical
manifestation and its aggressiveness. Developing a novel diagnostic and prognostic …

Early studies have shown how aberrantly expressed microRNAs are a hallmark of several
diseases like cancer. MicroRNA expression profiling was shown to be associated with …

Mature microRNAs (miRNAs) are single-stranded RNA molecules of 20–23-nucleotide (nt)
length that control gene expression in many cellular processes. These molecules typically …

The origins of the mesenchymal cells participating in tissue repair and pathological
processes, notably tissue fibrosis, tumor invasiveness, and metastasis, are poorly …

Transitions between epithelial and mesenchymal states have crucial roles in embryonic
development. Emerging data suggest a role for these processes in regulating cellular …

The epithelial-to-mesenchymal transition (EMT) produces cancer cells that are invasive,
migratory, and exhibit stem cell characteristics, hallmarks of cells that have the potential to …

Cadherins are homophilic adhesion molecules with important functions in cell-cell adhesion,
tissue morphogenesis, and cancer. In epithelial cells, E-cadherin accumulates at areas of …

Mature microRNAs (miRNAs) are single‐stranded RNA molecules of 20–23 nucleotide (nt)
length that control gene expression in many cellular processes. These molecules typically …

The transforming growth factor‐beta (TGFβ) superfamily encompasses widespread and
evolutionarily conserved polypeptide growth factors that regulate and orchestrate growth …