At coitus, human sperm are deposited into the anterior vagina, where, to avoid vaginal acid
and immune responses, they quickly contact cervical mucus and enter the cervix. Cervical …

The world's population is increasing at an alarming rate and is projected to reach nine billion
by 2050. Despite this, 15% of couples world-wide remain childless because of infertility. Few …

During mating, males transfer seminal proteins and peptides, along with sperm, to their
mates. In Drosophila melanogaster, seminal proteins made in the male's accessory gland …

Successful reproduction requires contributions from both the male and the female. In
Drosophila, contributions from the male include accessory gland proteins (Acps) that are …

The study of insect seminal fluid proteins provides a unique window upon adaptive evolution
in action. The seminal fluid of Drosophila melanogaster contains over 80 proteins and …

In animals with internal fertilization, ovulation and female sperm storage are essential steps
in reproduction. While these events are often required for successful fertilization, they remain …

Successful reproduction is critical to pass genes to the next generation. Seminal proteins
contribute to important reproductive processes that lead to fertilization in species ranging …

Proteins in the seminal fluid of animals with internal fertilization effect numerous responses
in mated females that impact both male and female fertility. Among these proteins is the …

Proteases and protease inhibitors have been identified in the ejaculates of animal taxa
ranging from invertebrates to mammals and form a major protein class among Drosophila …

Serpins compose the largest superfamily of peptidase inhibitors and are well known as
regulators of hemostasis and thrombolysis. Studies using model organisms, from plants to …