Reproduction involves a wide range of biological processes, including organ formation and
development, neuroendocrine regulation, hormone production, and meiosis and mitosis …

The pubertal development onset is controlled by a network of genes that regulate the
gonadotropin releasing hormone (GnRH) pulsatile release and the subsequent increase of …

Background We have recently demonstrated a causal link between loss of gonadotropin-
releasing hormone (GnRH), the master molecule regulating reproduction, and cognitive …

Hypothalamic gonadotropin-releasing hormone (GnRH) neurons regulate fertility and
integrate hormonal status with environmental cues to ensure reproductive success. Here we …

Pulsatile secretion of gonadotropin-releasing hormone (GnRH) is essential for activating
and maintaining the function of the hypothalamic–pituitary–gonadal axis, which controls the …

Reproduction in mammals is an extremely energy-intensive process and is therefore tightly
controlled by the body's energy status. Changes in the nutritional status of the body cause …

Background The maturation of the hypothalamic-pituitary-gonadal (HPG) axis is crucial for
the establishment of reproductive function. In female mice, neuronal nitric oxide synthase …

Gonadal steroid feedback regulates the brain's patterned secretion of gonadotropin-
releasing hormone (GnRH). Negative feedback, which occurs in males and during the …

An individual's nutritional status has a powerful effect on sexual maturation. Puberty onset is
delayed in response to chronic energy insufficiency and is advanced under energy …

Infants born with severe central disorders of the hypothalamic‐pituitary‐gonadal axis
leading to gonadotropin deficiency not only lack pubertal development in adolescence, but …