[HTML][HTML] The role of VEGF in cancer-induced angiogenesis and research progress of drugs targeting VEGF

S Ghalehbandi, J Yuzugulen, MZI Pranjol… - European Journal of …, 2023 - Elsevier
Angiogenesis is a double-edged sword; it is a mechanism that defines the boundary
between health and disease. In spite of its central role in physiological homeostasis, it …

Molecular mechanism of VEGF and its role in pathological angiogenesis

A Ahmad, MI Nawaz - Journal of Cellular Biochemistry, 2022 - Wiley Online Library
Over the last seven decades, a significant scientific contribution took place in the delineation
of the implications of vascular endothelial‐derived growth factor (VEGF) in the processes of …

[HTML][HTML] Therapeutic targeting of angiogenesis molecular pathways in angiogenesis-dependent diseases

A Fallah, A Sadeghinia, H Kahroba, A Samadi… - Biomedicine & …, 2019 - Elsevier
Angiogenesis is a critical step in the progression of almost all human malignancies and
some other life-threatening diseases. Anti-angiogenic therapy is a novel and effective …

[HTML][HTML] Magnesium alloys for orthopedic applications: A review on the mechanisms driving bone healing

N Wang, S Yang, H Shi, Y Song, H Sun, Q Wang… - Journal of Magnesium …, 2022 - Elsevier
Magnesium (Mg) alloys have attracted a wealth of attention in orthopedic fields for their
superior mechanical properties, degradability, and excellent biocompatibility. Consistently …

Role of melatonin in controlling angiogenesis under physiological and pathological conditions

Q Ma, RJ Reiter, Y Chen - Angiogenesis, 2020 - Springer
Angiogenesis depends on proangiogenic and anti-angiogenic molecules that regulate
endothelial cell proliferation and migration. Well-regulated angiogenesis plays a pivotal role …

Perfused 3D angiogenic sprouting in a high-throughput in vitro platform

V Van Duinen, D Zhu, C Ramakers, AJ Van Zonneveld… - Angiogenesis, 2019 - Springer
Angiogenic sprouting, the growth of new blood vessels from pre-existing vessels, is
orchestrated by cues from within the cellular microenvironment, such as biochemical …

[HTML][HTML] Vascular pathobiology in chronic liver disease and cirrhosis–current status and future directions

Y Iwakiri, V Shah, DC Rockey - Journal of hepatology, 2014 - Elsevier
Chronic liver disease is associated with remarkable alterations in the intra-and extrahepatic
vasculature. Because of these changes, the fields of liver vasculature and portal …

Mesenchymal stem/stromal cells as a pharmacological and therapeutic approach to accelerate angiogenesis

A Bronckaers, P Hilkens, W Martens, P Gervois… - Pharmacology & …, 2014 - Elsevier
Mesenchymal stem cells or multipotent stromal cells (MSCs) have initially captured attention
in the scientific world because of their differentiation potential into osteoblasts …

Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation

G del Monte-Nieto, M Ramialison, AAS Adam, B Wu… - Nature, 2018 - nature.com
In vertebrate hearts, the ventricular trabecular myocardium develops as a sponge-like
network of cardiomyocytes that is critical for contraction and conduction, ventricular …

Endothelial Ca2+ Signaling, Angiogenesis and Vasculogenesis: Just What It Takes to Make a Blood Vessel

F Moccia, S Negri, M Shekha, P Faris… - International journal of …, 2019 - mdpi.com
It has long been known that endothelial Ca2+ signals drive angiogenesis by recruiting
multiple Ca2+-sensitive decoders in response to pro-angiogenic cues, such as vascular …