Antimicrobial-resistant ESKAPE (E nterococcus faecium, S taphylococcus aureus, K
lebsiella pneumoniae, A cinetobacter baumannii, P seudomonas aeruginosa, and E …

Ceftolozane/tazobactam and ceftazidime/avibactam are 2 novel β-lactam/β-lactamase
combination antibiotics. The antimicrobial spectrum of activity of these antibiotics includes …

Background: Previous evidence-based guidelines on the management of intra-abdominal
infection (IAI) were published by the Surgical Infection Society (SIS) in 1992, 2002, and …

Background. Klebsiella pneumoniae is an opportunistic pathogen and leading cause of
hospital-associated infections. Intensive care unit (ICU) patients are particularly at risk …

It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

Scope These ESCMID guidelines address the targeted antibiotic treatment of third-
generation cephalosporin-resistant Enterobacterales (3GCephRE) and carbapenem …

Antibiotic resistance can be reduced by using antibiotics prudently based on guidelines of
antimicrobial stewardship programs (ASPs) and various data such as pharmacokinetic (PK) …

Carbapenem antibiotics are generally considered to be the most potent group of
antimicrobial agents with proven efficacy in the treatment of patients with severe bacterial …

Extended-spectrum β-lactamases (ESBLs) are a group of plasmid-mediated, diverse,
complex and rapidly evolving enzymes that are posing a major therapeutic challenge today …

Extended-spectrum β-lactamases (ESBLs) are a rapidly evolving group of β-lactamases
which share the ability to hydrolyze third-generation cephalosporins and aztreonam yet are …