[HTML][HTML] Tertiary lymphoid structures in diseases: immune mechanisms and therapeutic advances
L Zhao, S Jin, S Wang, Z Zhang, X Wang… - … and Targeted Therapy, 2024 - nature.com
Tertiary lymphoid structures (TLSs) are defined as lymphoid aggregates formed in non-
hematopoietic organs under pathological conditions. Similar to secondary lymphoid organs …
hematopoietic organs under pathological conditions. Similar to secondary lymphoid organs …
[HTML][HTML] Immunotherapy with immune checkpoint inhibitors and predictive biomarkers in malignant mesothelioma: work still in progress
M Perrino, F De Vincenzo, N Cordua, F Borea… - Frontiers in …, 2023 - frontiersin.org
Malignant mesothelioma (MM) is a rare and aggressive neoplasm, usually associated with a
poor prognosis (5 years survival rate< 10%). For unresectable disease, platinum and …
poor prognosis (5 years survival rate< 10%). For unresectable disease, platinum and …
Single-Cell View of Tumor Microenvironment Gradients in Pleural Mesothelioma
Immunotherapies have shown great promise in pleural mesothelioma (PM), yet most
patients still do not achieve significant clinical response, highlighting the importance of …
patients still do not achieve significant clinical response, highlighting the importance of …
[HTML][HTML] Benefits and challenges of inhibiting EZH2 in malignant pleural mesothelioma
Simple Summary Malignant pleural mesothelioma (MPM) is an aggressive cancer linked to
asbestos exposure with an extremely poor outcome. Despite the recent approval of immune …
asbestos exposure with an extremely poor outcome. Despite the recent approval of immune …
[HTML][HTML] Immunotherapy of mesothelioma: the evolving change of a long-standing therapeutic dream
L Calabrò, G Bronte, F Grosso, L Cerbone… - Frontiers in …, 2024 - frontiersin.org
Pleural mesothelioma (PM) is an aggressive and rare disease, characterized by a very poor
prognosis. For almost two decades, the world standard treatment regimen for unresectable …
prognosis. For almost two decades, the world standard treatment regimen for unresectable …
[HTML][HTML] Genomic Landscape of Pleural Mesothelioma and Therapeutic Aftermaths
A Nash, J Creaney - Current oncology reports, 2023 - Springer
Abstract Purpose of Review In this article, we provide a comprehensive analysis of recent
progress in the genetic characterisation of pleural mesothelioma, and the translation of …
progress in the genetic characterisation of pleural mesothelioma, and the translation of …
[HTML][HTML] The Italian experience in the development of mesothelioma registries: a pathway for other countries to address the negative legacy of asbestos
C Magnani, C Mensi, A Binazzi, D Marsili… - International Journal of …, 2023 - mdpi.com
Asbestos (all forms, including chrysotile, crocidolite, amosite, tremolite, actinolite, and
anthophyllite) is carcinogenic to humans and causally associated with mesothelioma and …
anthophyllite) is carcinogenic to humans and causally associated with mesothelioma and …
[HTML][HTML] Tumor treating fields affect mesothelioma cell proliferation by exerting histotype-dependent cell cycle checkpoint activations and transcriptional modulations
L Mannarino, F Mirimao, N Panini, L Paracchini… - Cell Death & …, 2022 - nature.com
Although clinical antitumor activity of Tumor Treating Fields (TTFields) has been reported in
malignant pleural mesothelioma (MPM) patients, the mechanisms behind the different …
malignant pleural mesothelioma (MPM) patients, the mechanisms behind the different …
[HTML][HTML] Tertiary Lymphoid Structures in Microorganism-Related Cancer
S Deng, X Yang, L He, Y Hou, H Meng - Cancers, 2024 - mdpi.com
Simple Summary The role of tertiary lymphoid structures (TLSs) in cancer has been
extensively studied, including predicting good prognosis and immunotherapy efficacy …
extensively studied, including predicting good prognosis and immunotherapy efficacy …
[HTML][HTML] Current State-of-the-Art Therapy for Malignant Pleural Mesothelioma and Future Options Centered on Immunotherapy
S Cedres, A Valdivia, P Iranzo, A Callejo, N Pardo… - Cancers, 2023 - mdpi.com
Simple Summary Advances in malignant pleural mesothelioma research have led to the
approval of first-line immunotherapies and the development of numerous trials of new first …
approval of first-line immunotherapies and the development of numerous trials of new first …