Neonatal hypoxia ischaemia: mechanisms, models, and therapeutic challenges

LJ Millar, L Shi, A Hoerder-Suabedissen… - Frontiers in cellular …, 2017 - frontiersin.org
Neonatal hypoxia-ischaemia (HI) is the most common cause of death and disability in
human neonates, and is often associated with persistent motor, sensory, and cognitive …

Pathophysiology of sleep apnea

JA Dempsey, SC Veasey, BJ Morgan… - Physiological …, 2010 - journals.physiology.org
Sleep-induced apnea and disordered breathing refers to intermittent, cyclical cessations or
reductions of airflow, with or without obstructions of the upper airway (OSA). In the presence …

Epidemiology-driven neurodevelopmental animal models of schizophrenia

U Meyer, J Feldon - Progress in neurobiology, 2010 - Elsevier
Human epidemiological studies have provided compelling evidence that the risk of
developing schizophrenia is significantly enhanced following prenatal and/or perinatal …

Intermittent hypoxic episodes in preterm infants: do they matter?

RJ Martin, K Wang, Ö Köroğlu, J Di Fiore, P Kc - Neonatology, 2011 - karger.com
Intermittent hypoxic episodes are typically a consequence of immature respiratory control
and remain a troublesome challenge for the neonatologist. Furthermore, their frequency and …

Obstructive sleep apnea and dyslipidemia: from animal models to clinical evidence

D Barros, F García-Río - Sleep, 2019 - academic.oup.com
Lipid metabolism deregulation constitutes the pathogenic basis for the development of
atherosclerosis and justifies a high incidence of cardiovascular-related morbidity and …

Tourette syndrome and tic disorders: a decade of progress

JE Swain, L Scahill, PJ Lombroso, RA King… - Journal of the American …, 2007 - Elsevier
OBJECTIVE:: This is a review of progress made in the understanding of Tourette syndrome
(TS) during the past decade including models of pathogenesis, state-of-the-art assessment …

Effects of caffeine on intermittent hypoxia in infants born prematurely: a randomized clinical trial

LM Rhein, NR Dobson, RA Darnall, MJ Corwin… - JAMA …, 2014 - jamanetwork.com
Importance Preterm infants have immature respiratory control and resulting intermittent
hypoxia (IH). The extent of IH after stopping routine caffeine treatment and the potential for …

The polymorphic and contradictory aspects of intermittent hypoxia

I Almendros, Y Wang, D Gozal - American Journal of …, 2014 - journals.physiology.org
Intermittent hypoxia (IH) has been extensively studied during the last decade, primarily as a
surrogate model of sleep apnea. However, IH is a much more pervasive phenomenon in …

Critical age windows for neurodevelopmental psychiatric disorders: evidence from animal models

EM Marco, S Macrì, G Laviola - Neurotoxicity research, 2011 - Springer
A disruption in normal brain development has been hypothesized to contribute to the
aetiology of major psychiatric disorders. According to the 'double-hit'hypothesis, mutant …

Cognition, sleep and respiration in at-risk children treated for obstructive sleep apnoea

HE Montgomery-Downs, VM Crabtree… - European Respiratory …, 2005 - Eur Respiratory Soc
Sleep-disordered breathing in children has been associated with cognitive impairment. The
purpose of this study was to examine the impact of tonsillectomy and adenoidectomy (T&A) …