Chitosan based bioadhesives for biomedical applications: A review

H Hamedi, S Moradi, SM Hudson, AE Tonelli… - Carbohydrate …, 2022 - Elsevier
Due to the promising properties of chitosan for biomedical engineering applications like
biodegradability, biocompatibility, and non-toxicity, it is one of the most interesting …

[HTML][HTML] Multiple roles of chitosan in mucosal drug delivery: an updated review

P Mura, F Maestrelli, M Cirri, N Mennini - Marine Drugs, 2022 - mdpi.com
Chitosan (CS) is a linear polysaccharide obtained by the deacetylation of chitin, which, after
cellulose, is the second biopolymer most abundant in nature, being the primary component …

[HTML][HTML] Buccal films: A review of therapeutic opportunities, formulations & relevant evaluation approaches

L Shipp, F Liu, L Kerai-Varsani, TC Okwuosa - Journal of Controlled …, 2022 - Elsevier
The potential of the mucoadhesive film technology is hard to ignore, owing to perceived
superior patient acceptability versus buccal tablets, and significant therapeutic opportunities …

Recent advances of oral film as platform for drug delivery

M He, L Zhu, N Yang, H Li, Q Yang - International Journal of Pharmaceutics, 2021 - Elsevier
Orally drug delivery film has received extensive interest duo to a distinct set of its
advantageous properties compared to the traditional orally administered dosages, including …

Fabrication of mucoadhesive buccal films for local administration of ketoprofen and lidocaine hydrochloride by combining fused deposition modeling and inkjet …

GK Eleftheriadis, PK Monou, N Bouropoulos… - Journal of …, 2020 - Elsevier
In the area of developing oromucosal drug delivery systems, mucoadhesive buccal films are
the most promising formulations for either systemic or local drug delivery. The current study …

[HTML][HTML] 3d printed buccal films for prolonged-release of propranolol hydrochloride: Development, characterization and bioavailability prediction

M Jovanović, M Petrović, S Cvijić, N Tomić… - Pharmaceutics, 2021 - mdpi.com
Gelatin-polyvinylpyrrolidone (PVP) and gelatin-poly (vinyl alcohol)(PVA) mucoadhesive
buccal films loaded with propranolol hydrochloride (PRH) were prepared by semi-solid …

[HTML][HTML] Preparation, in vitro and in vivo evaluation of chitosan-sodium alginate-ethyl cellulose polyelectrolyte film as a novel buccal mucosal delivery vehicle

S Wang, Z Gao, L Liu, M Li, A Zuo, J Guo - European Journal of …, 2022 - Elsevier
This paper describes the development of a film comprising chitosan (CS), sodium alginate
(SA), and ethyl cellulose (EC) for buccal mucosal administration. A film of CS-SA …

[HTML][HTML] Polysaccharide-based drug delivery systems for the treatment of periodontitis

N Baranov, M Popa, LI Atanase, DL Ichim - Molecules, 2021 - mdpi.com
Periodontal diseases are worldwide health problems that negatively affect the lifestyle of
many people. The long-term effect of the classical treatments, including the mechanical …

[HTML][HTML] Polymeric carriers for delivery systems in the treatment of chronic periodontal disease

M Zięba, P Chaber, K Duale, M Martinka Maksymiak… - Polymers, 2020 - mdpi.com
Periodontitis (PD) is a chronic inflammatory disease of periodontal tissues caused by
pathogenic microorganisms and characterized by disruption of the tooth-supporting …

Chitosan-based buccal mucoadhesive patches to enhance the systemic bioavailability of tizanidine

MD Arpa, NÜ Okur, MK Gök, S Özgümüş… - International Journal of …, 2023 - Elsevier
Tizanidine hydrochloride (TZN) is a muscle relaxant used to treat a variety of disorders such
as painful muscle spasms and chronic spasticity. TZN has low oral bioavailability due to …