Putting the spotlight back on plant suspension cultures

RB Santos, R Abranches, R Fischer, M Sack… - Frontiers in plant …, 2016 - frontiersin.org
Plant cell suspension cultures have several advantages that make them suitable for the
production of recombinant proteins. They can be cultivated under aseptic conditions using …

Low Protease Content in Medicago truncatula Cell Cultures Facilitates Recombinant Protein Production

RB Santos, B Chandrasekar, MK Mandal… - Biotechnology …, 2018 - Wiley Online Library
Medicago truncatula is an established model for studying legume biology. More recently, it
has also been exploited as a Molecular Farming platform for the production of recombinant …

Addition of a histone deacetylase inhibitor increases recombinant protein expression in Medicago truncatula cell cultures

RB Santos, AS Pires, R Abranches - Scientific reports, 2017 - nature.com
Plant cell cultures are an attractive platform for the production of recombinant proteins. A
major drawback, hindering the establishment of plant cell suspensions as an industrial …

[HTML][HTML] Prospects for the production of recombinant therapeutic proteins and peptides in plants: Special focus on Angiotensin I-Converting Enzyme Inhibitory (ACEI) …

C Gomes, F Oliveira, SI Vieira… - Genetic engineering-A …, 2019 - intechopen.com
Molecular pharming is a cost-effective, scalable, and safe system to produce high-quality
and biologically active recombinant therapeutic proteins. Thus, plants are emerging …

Synthesis and biological effects of small molecule enhancers for improved recombinant protein production in plant cell cultures

BA Rebelo, RB Santos, OS Ascenso, AC Nogueira… - Bioorganic …, 2020 - Elsevier
Histone deacetylases are involved in chromatin remodelling and thus play a vital role in the
epigenetic regulation of gene expression. HDAC inhibitors alter the acetylation status of …

Generation of transgenic cell suspension cultures of the model legume Medicago truncatula: a rapid method for Agrobacterium mediated gene transfer

RB Santos, AS Pires, RAL van der Hoorn… - Plant Cell, Tissue and …, 2019 - Springer
Plant cell suspension cultures are used in basic research and applied biotechnology. In both
cases, the transfer and stable integration of heterologous genes is a required technique …

O cardo ea indústria de queijo: ferramentas biotecnológicas para a produção de enzimas utilizadas na coagulação do leite

A Folgado, R Abranches - Revista de Ciências Agrárias, 2019 - revistas.rcaap.pt
Em Portugal, como noutros países da bacia mediterrânica, a planta de cardo (Cynara
cardunculus L.) tem sido utilizada desde tempos antigos para diversas aplicações nas …

Otimização da produção de proteínas recombinantes em culturas de células vegetais: edição de genoma de células de tabaco BY-2 através de CRISPR-Cas9

AR de Jesus Nogueira - 2017 - search.proquest.com
A utilização de plantas transgénicas para a produção em larga escala de proteínas
recombinantes com valor comercial e farmacêutico tem merecido destaque como alternativa …

Thistle and the cheese industry: biotechnological tools for the production of enzymes for milk coagulation.

A Folgado, R Abranches - 2019 - cabidigitallibrary.org
In Portugal, as in other countries of the Mediterranean basin, the thistle plant (Cynara
cardunculus L.) has been used since ancient times for several applications in the food and …

[PDF][PDF] The Expression of Circadian Clock Gene Promoters in Arabidopsis Callus.

K Laosuntisuk - 2018 - repository.lib.ncsu.edu
LAOSUNTISUK, KANJANA. The Expression of Circadian Clock Gene Promoters in Arabidopsis
Callus (Under the direction of Dr Page 1 ABSTRACT LAOSUNTISUK, KANJANA. The …