Objective To review the current knowledge on bone health in patients with hemophilia A and
the underlying pathogenetic mechanisms. Data Sources Original research articles, meta …

Hemophilia A is an X-linked hereditary disorder that results from deficient coagulation factor
VIII (FVIII) activity, leading to spontaneous bleeding episodes, particularly in joints and …

Introduction Emicizumab prophylaxis significantly reduces bleeding events; however, the
associated impact on bone/joint health is unknown. Aim To explore the effect of emicizumab …

Introduction Progressive arthropathy is the main cause of morbidity in patients with severe
haemophilia. Diagnostic imaging can detect even subclinical arthropathy and impact …

Introduction The relationship between severe hemophilia and osteoporosis has been well
established in the literature. However, although the importance of its prevention in order to …

Background: The study aimed to evaluate radiomorphometric indices derived from
panoramic X-rays and selected blood markers of bone turnover and neutrophil extracellular …

Introduction Patients with haemophilia (PWH) may have lower bone mineral density (BMD).
The risk of low BMD in PWH has not been comprehensively analysed. This study aimed to …

Introduction People with hemophilia risk osteoporosis more than healthy people, which may
be related to specific factors. Methods This case-control study included 53 patients with …

Background The higher life expectancy in patients with hemophilia (PWH) due to better care
has increased the incidence of age-related complications such as osteoporosis. This study …

Abstract Background: Hemophilia A (HA) and B (HB) are inherited bleeding disorders due to
the partial or total deficiency of coagulation factor (F) VIII or FIX, respectively. It is associated …