Depression is a recurrent, heterogeneous mood disorder occurring in more than 260 million
people worldwide. Gut microbiome dysbiosis is associated with the development of …

The proper functioning of any protein depends on its three dimensional conformation which
is achieved by the accurate folding mechanism. Keeping away from the exposed stress …

(1) Objective: Considering that current knowledge of mechanisms involved in the molecular
pathogenesis of Social Anxiety Disorder (SAD) is limited, we conducted a systematic review …

The onset of puberty, which is under the control of the hypothalamic–pituitary–gonadal
(HPG) axis, is influenced by various factors, including obesity, which has been associated …

α-Synuclein (α-Syn) fibrillation is a prominent contributor to neuronal deterioration and plays
a significant role in the advancement of Parkinson's Disease (PD). Considering this, the …

While exaptation is most impressive when links between very dissimilar contexts are
established, it can be even more pervasive when the previously unestablished connection …

Background Recently, a variety of studies using different neuroimaging techniques
attempted to identify the existence of a brain endophenotype in people with gender …

Direct studies focusing on the human brain are difficult to plan and conduct due to ethical
and practical reasons. The advent of human pluripotent stem cell (hPSC)-derived neurons …

Deposition of toxic protein inclusions is a common hallmark of many neurodegenerative
disorders including Alzheimer's disease, Parkinson disease etc. N-acetylaspartate (NAA) is …

Osmolytes alter the stability and aggregation of proteins. The effect of mixture of osmolytes is
generally not a simple additive of their individual effects. Here, we examine the effect of …