[HTML][HTML] CNS pharmacology of NKCC1 inhibitors
W Loescher, K Kaila - Neuropharmacology, 2022 - Elsevier
Abstract The Na–K–2Cl cotransporter NKCC1 and the neuron-specific K–Cl cotransporter
KCC2 are considered attractive CNS drug targets because altered neuronal chloride …
KCC2 are considered attractive CNS drug targets because altered neuronal chloride …
[HTML][HTML] The role of SLC12A family of cation-chloride cotransporters and drug discovery methodologies
The solute carrier family 12 (SLC12) of cation-chloride cotransporters (CCCs) comprises
potassium chloride cotransporters (KCCs, eg KCC1, KCC2, KCC3, and KCC4)-mediated …
potassium chloride cotransporters (KCCs, eg KCC1, KCC2, KCC3, and KCC4)-mediated …
Progress report on new antiepileptic drugs: a summary of the Sixteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVI): II. Drugs in more …
M Bialer, SI Johannessen, MJ Koepp, RH Levy… - …, 2022 - Wiley Online Library
Abstract The Sixteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT
XVI) was held in Madrid, Spain on May 22–25, 2022 and was attended by 157 delegates …
XVI) was held in Madrid, Spain on May 22–25, 2022 and was attended by 157 delegates …
Computational screening of phytochemicals for anti-cancer drug discovery
KS Turabi, S Bhupal, S Layek, S Garse… - … Tools and Databases in …, 2023 - Elsevier
Cancer remains to be one of the most prevalent diseases, affecting the lives of millions of
people worldwide. Despite wreaking havoc for centuries, a definitive and effective course of …
people worldwide. Despite wreaking havoc for centuries, a definitive and effective course of …
Visible Light‐Promoted Catalyst‐Free (VLCF) Scalable Synthesis of Novel Derivatives of Isoniazid and Maleimide
S Iqbal, MK Hussain, B Singh, MR Zaheer… - …, 2024 - Wiley Online Library
We have developed a Visible Light Promoted Catalyst‐Free (VLCF) approach to synthesize
novel conjugates of Isoniazid and Maleimide. This method involves the formation of an …
novel conjugates of Isoniazid and Maleimide. This method involves the formation of an …
Identification of dual inhibitors for EGFR (T790M/C797S) and VEGFR-2 in Non-Small Cell Lung Cancer from Moringa oleifera derived phytochemicals: An In-silico …
MMR Munna, MTT Tusar, SS Shanta, MH Ahmed… - 2024 - researchsquare.com
Non-small-cell lung cancer (NSCLC) is the leading cause of cancer-related mortality on a
global scale for both men and women. At present, the treatment of NSCLC involves the use …
global scale for both men and women. At present, the treatment of NSCLC involves the use …