[HTML][HTML] Inducing angiogenesis, a key step in cancer vascularization, and treatment approaches

H Saman, SS Raza, S Uddin, K Rasul - Cancers, 2020 - mdpi.com
Angiogenesis is a term that describes the formation of new blood and lymphatic vessels from
a pre-existing vasculature. This allows tumour cells to acquire sustenance in the form of …

[PDF][PDF] Matricryptins derived from collagens and proteoglycans

S Ricard-Blum, L Ballut - Front Biosci, 2011 - article.imrpress.com
Controlled proteolysis of extracellular matrix components releases bioactive fragments or
unmasks cryptic sites that play key roles in controlling various physio-pathological …

Zinc reduces collagen degradation in demineralized human dentin explants

R Osorio, M Yamauti, E Osorio, ME Ruiz-Requena… - Journal of dentistry, 2011 - Elsevier
OBJECTIVES: Dentin matrix metalloproteinases are implicated in the pathogenesis of caries
and contribute to collagen degradation in resin–dentin interfaces. The objective was to …

A Zn-doped etch-and-rinse adhesive may improve the mechanical properties and the integrity at the bonded-dentin interface

M Toledano, S Sauro, I Cabello, T Watson, R Osorio - Dental Materials, 2013 - Elsevier
Objective The objective of the study was to determine if zinc-doped etch-and-rinse dentin
adhesive may induce therapeutic effects within the resin–dentin interface. Methods Human …

A ZnO-doped adhesive reduced collagen degradation favouring dentine remineralization

M Toledano, M Yamauti, ME Ruiz-Requena, R Osorio - Journal of Dentistry, 2012 - Elsevier
OBJECTIVES: The objective of the study was to determine the efficacy of a ZnO-doped etch
and rinse adhesive in decreasing MMPs-mediated collagen degradation at the resin …

[HTML][HTML] Matricryptins network with matricellular receptors at the surface of endothelial and tumor cells

S Ricard-Blum, SD Vallet - Frontiers in pharmacology, 2016 - frontiersin.org
The extracellular matrix (ECM) is a source of bioactive fragments called matricryptins or
matrikines resulting from the proteolytic cleavage of extracellular proteins (eg, collagens …

Endostar attenuates melanoma tumor growth via its interruption of b-FGF mediated angiogenesis

L Xiao, SC Yang, J Hao, X Yuan, W Luo, L Jiang, Y Hu… - Cancer letters, 2015 - Elsevier
To develop optimal therapeutics is one of the hotspots in both clinical and basic melanoma
studies. Previous studies indicate that fibroblast growth factors (b-FGF/FGF-2), an …

Load cycling enhances bioactivity at the resin–dentin interface

M Toledano, FS Aguilera, S Sauro, I Cabello, E Osorio… - Dental Materials, 2014 - Elsevier
Objectives The purpose of this study was to evaluate if mechanical loading promotes
bioactivity at the resin interface after bonding with three different adhesive approaches …

[HTML][HTML] Recombinant human endostatin enhances the radioresponse in esophageal squamous cell carcinoma by normalizing tumor vasculature and reducing …

H Zhu, X Yang, Y Ding, J Liu, J Lu, L Zhan, Q Qin… - Scientific reports, 2015 - nature.com
The aim of this study was to investigate the effect of recombinant human endostatin (rh-
Endo) in combination with radiation therapy (RT) on esophageal squamous cell carcinoma …

[HTML][HTML] Zn-Containing adhesives facilitate collagen protection and remineralization at the resin-dentin interface: A narrative review

M Toledano, M Toledano-Osorio, M Hannig… - Polymers, 2022 - mdpi.com
This is a narrative review of the literature assessing the potential effectiveness of doping
dentin polymeric adhesives with zinc compounds in order to improve bonding efficacy …