Enzymatically oxidized lipids are a specific group of biomolecules that function as key
signaling mediators and hormones, regulating various cellular and physiological processes …

After more than a century, aspirin remains one of the most commonly used drugs in western
medicine. Although mainly used for its anti-thrombotic, anti-pyretic, and analgesic properties …

5-Lipoxygenase (5-LOX) plays a key role in inflammation through the biosynthesis of
leukotrienes and other lipid mediators. Current evidence suggests that dietary (poly) …

Cardiovascular diseases are the leading cause of global deaths, and many risk factors
contribute to their pathogenesis. In this context, prostanoids, which derive from arachidonic …

Simple Summary Glioblastoma multiforme is a brain tumor with a very unfavorable
prognosis, where the vast majority of patients do not survive a year after diagnosis. One line …

Oxylipins, the oxidation products of unsaturated fatty acids (FA), are potent endogenous
mediators being involved in the regulation of various biological processes such as …

Highlights•The extreme diversity of the lipidome poses a significant analytical challenge.•A
variety of mass spectrometry-based approaches exist for the analysis of lipids.•Combining …

C20-and C22-dihydroxy fatty acids (DiHFAs) are bioactive lipid mediators (LMs) in humans.
Among them, leukotrienes are inflammatory mediators, whereas resolvins generated by M2 …

Gintonin, newly extracted from ginseng, is a glycoprotein that acts as an exogenous
lysophosphatidic acid (LPA) receptor ligand. This study aimed to demonstrate the in vivo …

The incidence, prevalence, and hospitalization rates associated with cardiovascular
diseases (CVDs) are projected to increase substantially in the world. Understanding of the …