Therapeutic effects of green tea polyphenol (‒)-Epigallocatechin-3-Gallate (EGCG) in relation to molecular pathways controlling inflammation, oxidative stress, and …

D Mokra, M Joskova, J Mokry - International journal of molecular sciences, 2022 - mdpi.com
(‒)-Epigallocatechin-3-gallate (EGCG) is the most abundant polyphenol in green tea.
Thanks to multiple interactions with cell surface receptors, intracellular signaling pathways …

Potential protective mechanisms of green tea polyphenol EGCG against COVID-19

Z Zhang, X Zhang, K Bi, Y He, W Yan, CS Yang… - Trends in food science & …, 2021 - Elsevier
Background The world is in the midst of the COVID-19 pandemic. In this comprehensive
review, we discuss the potential protective effects of (−)-epigallocatechin-3-gallate (EGCG) …

[HTML][HTML] New insights into the mechanisms of polyphenols beyond antioxidant properties; lessons from the green tea polyphenol, epigallocatechin 3-gallate

HS Kim, MJ Quon, J Kim - Redox biology, 2014 - Elsevier
Green tea is rich in polyphenol flavonoids including catechins. Epigallocatechin 3-gallate
(EGCG) is the most abundant and potent green tea catechin. EGCG has been extensively …

Molecular understanding of Epigallocatechin gallate (EGCG) in cardiovascular and metabolic diseases

QY Eng, PV Thanikachalam, S Ramamurthy - Journal of …, 2018 - Elsevier
Ethnopharmacological relevance The compound epigallocatechin-3-gallate (EGCG), the
major polyphenolic compound present in green tea [Camellia sinensis (Theaceae], has …

Current evidence on the effect of dietary polyphenols intake on chronic diseases

C Costa, A Tsatsakis, C Mamoulakis, M Teodoro… - Food and Chemical …, 2017 - Elsevier
Polyphenols are secondary metabolites of plants. They comprise several antioxidant
compounds and they are generally considered to be involved in the defense against human …

Polyphenols: benefits to the cardiovascular system in health and in aging

S Khurana, K Venkataraman, A Hollingsworth, M Piche… - Nutrients, 2013 - mdpi.com
Numerous studies have demonstrated the importance of naturally occurring dietary
polyphenols in promoting cardiovascular health and emphasized the significant role these …

Targeting oxidative stress as a preventive and therapeutic approach for cardiovascular disease

Q Yan, S Liu, Y Sun, C Chen, S Yang, M Lin… - Journal of Translational …, 2023 - Springer
Cardiovascular diseases (CVDs) continue to exert a significant impact on global mortality
rates, encompassing conditions like pulmonary arterial hypertension (PAH), atherosclerosis …

Protective effect of epigallocatechin-3-gallate (EGCG) in diseases with uncontrolled immune activation: could such a scenario be helpful to counteract COVID-19?

M Menegazzi, R Campagnari, M Bertoldi… - International Journal of …, 2020 - mdpi.com
Some coronavirus disease 2019 (COVID-19) patients develop acute pneumonia which can
result in a cytokine storm syndrome in response to Severe Acute Respiratory Syndrome …

Cisplatin ototoxicity and protection: clinical and experimental studies

LP Rybak, D Mukherjea, S Jajoo… - The Tohoku journal of …, 2009 - jstage.jst.go.jp
Cisplatin is a chemotherapeutic agent that is widely used to treat a variety of malignant
tumors. Serious dose-limiting side effects like ototoxicity, nephrotoxicity and neurotoxicity …

Green tea polyphenol epigallocatechi3-gallate: Inflammation and arthritis

R Singh, N Akhtar, TM Haqqi - Life sciences, 2010 - Elsevier
A number of factors including inflammation and oxidative stress are believed to play a role in
the development of chronic joint diseases. Green tea has become a popular drink and is …