Efflux-mediated antifungal drug resistance

RD Cannon, E Lamping, AR Holmes… - Clinical microbiology …, 2009 - Am Soc Microbiol
Fungi cause serious infections in the immunocompromised and debilitated, and the
incidence of invasive mycoses has increased significantly over the last 3 decades. Slow …

Resistance to antifungals that target CYP51

JE Parker, AGS Warrilow, CL Price, JGL Mullins… - Journal of Chemical …, 2014 - Springer
Fungal diseases are an increasing global burden. Fungi are now recognised to kill more
people annually than malaria, whilst in agriculture, fungi threaten crop yields and food …

[HTML][HTML] Multisite validation of cryptococcal antigen lateral flow assay and quantification by laser thermal contrast

DR Boulware, MA Rolfes, R Rajasingham… - Emerging infectious …, 2014 - ncbi.nlm.nih.gov
Cryptococcal meningitis is common in sub-Saharan Africa. Given the need for data for a
rapid, point-of-care cryptococcal antigen (CRAG) lateral flow immunochromatographic assay …

[图书][B] Practical handbook of microbiology

LH Green, E Goldman - 2021 - books.google.com
Practical Handbook of Microbiology, 4th edition provides basic, clear and concise
knowledge and practical information about working with microorganisms. Useful to anyone …

Extracellular Vesicles Produced by Cryptococcus neoformans Contain Protein Components Associated with Virulence

ML Rodrigues, ES Nakayasu, DL Oliveira… - Eukaryotic …, 2008 - Am Soc Microbiol
Cryptococcus neoformans produces vesicles containing its major virulence factor, the
capsular polysaccharide glucuronoxylomannan (GXM). These vesicles cross the cell wall to …

[HTML][HTML] Systematic genetic analysis of virulence in the human fungal pathogen Cryptococcus neoformans

OW Liu, CD Chun, ED Chow, C Chen, HD Madhani… - Cell, 2008 - cell.com
The fungus Cryptococcus neoformans is a leading cause of mortality and morbidity among
HIV-infected individuals. We utilized the completed genome sequence and optimized …

Host immunity to Cryptococcus neoformans

S Rohatgi, L Pirofski - Future microbiology, 2015 - Future Medicine
Cryptococcosis is caused by the fungal genus Cryptococcus. Cryptococcosis, predominantly
meningoencephalitis, emerged with the HIV pandemic, primarily afflicting HIV-infected …

Iron regulation of the major virulence factors in the AIDS-associated pathogen Cryptococcus neoformans

WH Jung, A Sham, R White, JW Kronstad - PLoS biology, 2006 - journals.plos.org
Iron overload is known to exacerbate many infectious diseases, and conversely, iron
withholding is an important defense strategy for mammalian hosts. Iron is a critical cue for …

Treatment for HIV‐associated cryptococcal meningitis

MW Tenforde, AE Shapiro, B Rouse… - Cochrane Database …, 2018 - cochranelibrary.com
Background Cryptococcal meningitis is a severe fungal infection that occurs primarily in the
setting of advanced immunodeficiency and remains a major cause of HIV‐related deaths …

A link between virulence and homeostatic responses to hypoxia during infection by the human fungal pathogen Cryptococcus neoformans

CD Chun, OW Liu, HD Madhani - PLoS pathogens, 2007 - journals.plos.org
Fungal pathogens of humans require molecular oxygen for several essential biochemical
reactions, yet virtually nothing is known about how they adapt to the relatively hypoxic …