African trypanosomes are unicellular, eukaryotic parasites that live extracellularly in a wide
range of mammals, including humans. They have a surface coat, composed of variant …

Trypanosomes are a group of protozoan eukaryotes, many of which are major parasites of
humans and livestock. The genomes of trypanosomes and their modes of gene expression …

The protozoan Trypanosoma cruzi almost invariably establishes life-long infections in
humans and other mammals, despite the development of potent host immune responses …

Tetracycline-regulated ectopic gene expression [1, 2] has come to form the backbone of
transgenic manipulation of Trypanosoma brucei. It has been used for the expression of toxic …

The structural basis of mitosis, spindle organisation and chromosome segregation, in the
unicellular parasite Trypanosoma brucei is poorly understood. Here, using …

The morphological events involved in the Leishmania major promastigote cell cycle have
been investigated in order to provide a detailed description of the chronological processes …

Variant histones play critical roles in transcriptional activation and repression, DNA repair
and chromosome segregation. We have identified HTV, a single-copy gene in Trypanosoma …

The haploid nuclear genome of the African trypanosome, Trypanosoma brucei, is about 35
Mb and varies in size among different trypanosome isolates by as much as 25%. The …

Putative TTAGGG repeat-binding factor (TRF) homologues in the genomes of Trypanosoma
brucei, Trypanosoma cruzi, and Leishmania major were identified. They have significant …

African trypanosomes, such as Trypanosoma brucei, are protozoan parasites of mammals
that were first described over 100 hundred years ago. They have long been the subjects of …