Drug-Induced Nephrotoxicity: Clinical Impact and Preclinical in Vitro Models
The kidney is a major target for drug-induced toxicity. Drug-induced nephrotoxicity remains a
major problem in the clinical setting, where the use of nephrotoxic drugs is often …
major problem in the clinical setting, where the use of nephrotoxic drugs is often …
Advances in understanding and treating diabetic kidney disease: focus on tubulointerstitial inflammation mechanisms
C Xu, X Ha, S Yang, X Tian, H Jiang - Frontiers in Endocrinology, 2023 - frontiersin.org
Diabetic kidney disease (DKD) is a serious complication of diabetes that can lead to end-
stage kidney disease. Despite its significant impact, most research has concentrated on the …
stage kidney disease. Despite its significant impact, most research has concentrated on the …
The most promising biomarkers of allogeneic kidney transplant rejection
K Rogulska, I Wojciechowska-Koszko… - Journal of …, 2022 - Wiley Online Library
Clinical transplantology is a constantly evolving field of medicine. Kidney transplantation has
become standard clinical practice, and it has a significant impact on reducing mortality and …
become standard clinical practice, and it has a significant impact on reducing mortality and …
Tumour stroma‐derived lipocalin‐2 promotes breast cancer metastasis
Tumour cell‐secreted factors skew infiltrating immune cells towards a tumour‐supporting
phenotype, expressing pro‐tumourigenic mediators. However, the influence of lipocalin‐2 …
phenotype, expressing pro‐tumourigenic mediators. However, the influence of lipocalin‐2 …
Revisiting neutrophil gelatinase-associated lipocalin (NGAL) in cancer: saint or sinner?
B Bauvois, SA Susin - Cancers, 2018 - mdpi.com
Human neutrophil gelatinase-associated lipocalin (NGAL) is a glycoprotein present in a
wide variety of tissues and cell types. NGAL exists as a 25 kDa monomer, a 46 kDa …
wide variety of tissues and cell types. NGAL exists as a 25 kDa monomer, a 46 kDa …
Lipocalin-2 and iron trafficking in the tumor microenvironment
Iron is an essential element for virtually all organisms. It facilitates cell proliferation and
growth but also contributes to major hallmarks of cancer such as tumor initiation, growth, and …
growth but also contributes to major hallmarks of cancer such as tumor initiation, growth, and …
Novel biomarkers of acute kidney injury in chronic liver disease: Where do we stand after a decade of research?
RV Yewale, BS Ramakrishna - Hepatology Research, 2023 - Wiley Online Library
Acute kidney injury (AKI) is a frequently encountered complication in decompensated
chronic liver disease (CLD) with an estimated prevalence of 20%–50% among hospitalized …
chronic liver disease (CLD) with an estimated prevalence of 20%–50% among hospitalized …
[HTML][HTML] Subclinical aki and clinical outcomes in elderly patients undergoing cardiac surgery: Diagnostic utility of ngal versus standard creatinine increase criteria
M Marcello, GM Virzì, MJ Muciño-Bermejo… - Cardiorenal …, 2022 - karger.com
Background: Acute kidney injury (AKI) is a common and serious postoperative complication
in patients undergoing cardiac surgery and its incidence is particularly high among elderly …
in patients undergoing cardiac surgery and its incidence is particularly high among elderly …
Urine neutrophil gelatinase‐associated lipocalin to diagnose and characterize acute kidney injury in dogs
E Monari, R Troìa, L Magna, M Gruarin… - Journal of veterinary …, 2020 - Wiley Online Library
Background Urine neutrophil gelatinase‐associated lipocalin (NGAL) is a promising
biomarker of acute kidney injury (AKI) in dogs. Objectives To evaluate the utility of urinary …
biomarker of acute kidney injury (AKI) in dogs. Objectives To evaluate the utility of urinary …
Urinary versus plasma neutrophil gelatinase-associated lipocalin (NGAL) as a predictor of mortality for acute kidney injury in intensive care unit patients
Objective To examine urinary and plasma neutrophil gelatinase-associated lipocalin (NGAL)
levels in predicting ICU mortality. Design Prospective observational. Setting University …
levels in predicting ICU mortality. Design Prospective observational. Setting University …