Resveratrol attenuates manganese-induced oxidative stress and neuroinflammation through SIRT1 signaling in mice
L Cong, MY Lei, ZQ Liu, ZF Liu, Z Ma, K Liu, J Li… - Food and Chemical …, 2021 - Elsevier
Exposure to excess levels of manganese (Mn) leads to neurotoxicity. Increasing evidence
demonstrates that oxidative stress and neuroinflammation are important pathological causes …
demonstrates that oxidative stress and neuroinflammation are important pathological causes …
Caffeic acid phenethyl ester counteracts doxorubicin-induced chemobrain in Sprague-Dawley rats: Emphasis on the modulation of oxidative stress and …
Chemotherapy-induced cognitive dysfunction (chemobrain) is one of the major complaints
for cancer patients treated with chemotherapy such as Doxorubicin (DOX). The induction of …
for cancer patients treated with chemotherapy such as Doxorubicin (DOX). The induction of …
IRE1 signaling pathway mediates protective autophagic response against manganese-induced neuronal apoptosis in vivo and in vitro
C Liu, DY Yan, C Wang, Z Ma, Y Deng, W Liu… - Science of the Total …, 2020 - Elsevier
Overexposure to manganese (Mn) can result in neurotoxicity and is associated with
manganism, a Parkinson's-like neurological disorder. In addition, Mn can induce …
manganism, a Parkinson's-like neurological disorder. In addition, Mn can induce …
Epigallocatechin-3-gallate improves chronic alcohol-induced cognitive dysfunction in rats by interfering with neuro-inflammatory, cell death and oxido-nitrosative …
Alcohol consumption for a longer period of time is linked with neuronal damage and an
increase in inflammatory signaling resulting in cell death and dementia. Natural compounds …
increase in inflammatory signaling resulting in cell death and dementia. Natural compounds …
Ethanol exacerbates manganese‐induced oxidative/nitrosative stress, pro‐inflammatory cytokines, nuclear factor‐κB activation, and apoptosis induction in rat …
Manganese (Mn) exposure is causing public health concerns as well as heavy alcohol
consumption. This study investigates the mechanisms of neurotoxicity associated with Mn …
consumption. This study investigates the mechanisms of neurotoxicity associated with Mn …
Selenium abates manganese–induced striatal and hippocampal toxicity via abrogation of neurobehavioral deficits, biometal accumulation, oxidative stress …
Excessive exposure to manganese (Mn) is associated with neurotoxicity characterized by
oxidative stress, inflammation, and apoptosis induction. Selenium (Se) has been shown to …
oxidative stress, inflammation, and apoptosis induction. Selenium (Se) has been shown to …
Exogenous monosodium glutamate exacerbates lipopolysaccharide-induced neurobehavioral deficits, oxidative damage, neuroinflammation, and cholinergic …
Extensive experimental evidence points to neuroinflammation and oxidative stress as major
pathogenic events that initiate and drive the neurodegenerative process. Monosodium …
pathogenic events that initiate and drive the neurodegenerative process. Monosodium …
Alcohol exposure increases manganese accumulation in the brain and exacerbates manganese-induced neurotoxicity in mice
M Han, M Böhlke, T Maher, J Kim - Archives of Toxicology, 2021 - Springer
Environmental and occupational exposure to heavy metals remains one of the major
concerns in public health. Increased levels of manganese (Mn) pollution are associated with …
concerns in public health. Increased levels of manganese (Mn) pollution are associated with …
Bioinformatics analysis of candidate genes involved in ethanol-induced microtia pathogenesis based on a human genome database: GeneCards
Y Lin, Z Hu - International Journal of Pediatric Otorhinolaryngology, 2021 - Elsevier
Objective Ethanol used by women during pregnancy increases the risk for microtia in the
foetus. Traditionally, laboratory experiments and Mouse Genome Informatics (MGI) have …
foetus. Traditionally, laboratory experiments and Mouse Genome Informatics (MGI) have …
Preparatory work for the update of the tolerable upper intake levels for manganese
This technical report describes collection and appraisal of scientific evidence that could be
used to derive an upper intake level (UL) for manganese. Two systematic reviews were …
used to derive an upper intake level (UL) for manganese. Two systematic reviews were …