Exposure to excess levels of manganese (Mn) leads to neurotoxicity. Increasing evidence
demonstrates that oxidative stress and neuroinflammation are important pathological causes …

Chemotherapy-induced cognitive dysfunction (chemobrain) is one of the major complaints
for cancer patients treated with chemotherapy such as Doxorubicin (DOX). The induction of …

Overexposure to manganese (Mn) can result in neurotoxicity and is associated with
manganism, a Parkinson's-like neurological disorder. In addition, Mn can induce …

Alcohol consumption for a longer period of time is linked with neuronal damage and an
increase in inflammatory signaling resulting in cell death and dementia. Natural compounds …

Manganese (Mn) exposure is causing public health concerns as well as heavy alcohol
consumption. This study investigates the mechanisms of neurotoxicity associated with Mn …

Excessive exposure to manganese (Mn) is associated with neurotoxicity characterized by
oxidative stress, inflammation, and apoptosis induction. Selenium (Se) has been shown to …

Extensive experimental evidence points to neuroinflammation and oxidative stress as major
pathogenic events that initiate and drive the neurodegenerative process. Monosodium …

Environmental and occupational exposure to heavy metals remains one of the major
concerns in public health. Increased levels of manganese (Mn) pollution are associated with …

Objective Ethanol used by women during pregnancy increases the risk for microtia in the
foetus. Traditionally, laboratory experiments and Mouse Genome Informatics (MGI) have …

This technical report describes collection and appraisal of scientific evidence that could be
used to derive an upper intake level (UL) for manganese. Two systematic reviews were …