Naringin and naringenin polyphenols in neurological diseases: understandings from a therapeutic viewpoint

TB Emran, F Islam, N Nath, H Sutradhar, R Das, S Mitra… - Life, 2022 - mdpi.com
The glycosides of two flavonoids, naringin and naringenin, are found in various citrus fruits,
bergamots, tomatoes, and other fruits. These phytochemicals are associated with multiple …

The protective roles of citrus flavonoids, naringenin, and naringin on endothelial cell dysfunction in diseases

JA Adetunji, KD Fasae, AI Awe, OK Paimo… - Heliyon, 2023 - cell.com
The endothelial cells (ECs) make up the inner lining of blood vessels, acting as a barrier
separating the blood and the tissues in several organs. ECs maintain endothelium integrity …

Therapeutic potential of naringin in neurological disorders

S Ahmed, H Khan, M Aschner, MM Hasan… - Food and Chemical …, 2019 - Elsevier
Neurological illnesses are multifactorial incurable debilitating disorders that may cause
neurodegeneration. These diseases influence approximately 30 million people around the …

Geraniol attenuates behavioral and neurochemical impairments by inhibitions of HPA-axis and oxido-inflammatory perturbations in mice exposed to post-traumatic …

B Ben-Azu, OG Adebayo, EG Moke… - Journal of Psychiatric …, 2023 - Elsevier
Geraniol is an acyclic isoprenoid monoterpenoid analogue that has been shown to elicit
neuroprotective functions, primarily through its ability to stimulate antioxidant and anti …

[HTML][HTML] Polyphenols as novel interventions for depression: exploring the efficacy, mechanisms of action, and implications for future research

E Gamage, R Orr, N Travica, MM Lane… - Neuroscience & …, 2023 - Elsevier
Numerous animal and human studies have assessed the relationship between polyphenols
and outcomes related to depression. However, no comprehensive synthesis of the main …

Citrus maxima (Brum.) Merr. (Rutaceae): Bioactive Chemical Constituents and Pharmacological Activities

B Sapkota, HP Devkota… - … Based Complementary and …, 2022 - Wiley Online Library
Citrus maxima (Burm). Merr.(family Rutaceae), commonly known as Pomelo, is an
ethnomedicinally, pharmacologically, and phytochemically valued species. Various …

Diosgenin alleviates alcohol-mediated escalation of social defeat stress and the neurobiological sequalae

B Ben-Azu, EG Moke, LE Chris-Ozoko… - …, 2024 - Springer
Rationale Emerging evidence indicates that persistent alcohol consumption escalates
psychosocial trauma achieved by social defeat stress (SDS)-induced neurobiological …

Dissecting the relationship between neuropsychiatric and neurodegenerative disorders

R Gupta, D Advani, D Yadav, RK Ambasta… - Molecular …, 2023 - Springer
Neurodegenerative diseases (NDDs) and neuropsychiatric disorders (NPDs) are two
common causes of death in elderly people, which includes progressive neuronal cell death …

Naringin mediates adult hippocampal neurogenesis for antidepression via activating CREB signaling

C Gao, M Wu, Q Du, J Deng, J Shen - Frontiers in cell and …, 2022 - frontiersin.org
The brain-derived neurotrophic factor/tropomyosin receptor kinase B/cAMP response
element-binding protein (BDNF/TrkB/CREB) signaling pathway is a critical therapeutic target …

Preventive putative mechanisms involved in the psychopathologies of mice passively coping with psychosocial defeat stress by quercetin

PI Ugwu, B Ben-Azu, SU Ugwu, CI Uruaka… - Brain Research …, 2022 - Elsevier
Derangements of neuroimmune, neurotrophic and neurochemical homeostasis have
important implications in psychosocial stress-induced psychopathologies. Whether …