Harnessing endogenous stimuli for responsive materials in theranostics

AB Cook, P Decuzzi - ACS nano, 2021 - ACS Publications
Materials that respond to endogenous stimuli are being leveraged to enhance
spatiotemporal control in a range of biomedical applications from drug delivery to diagnostic …

Targeted drug delivery with polymers and magnetic nanoparticles: covalent and noncovalent approaches, release control, and clinical studies

K Ulbrich, K Hola, V Subr, A Bakandritsos… - Chemical …, 2016 - ACS Publications
Targeted delivery combined with controlled drug release has a pivotal role in the future of
personalized medicine. This review covers the principles, advantages, and drawbacks of …

pH-sensitive nano-systems for drug delivery in cancer therapy

J Liu, Y Huang, A Kumar, A Tan, S Jin, A Mozhi… - Biotechnology …, 2014 - Elsevier
Nanotechnology has been widely used in the development of new strategies for drug
delivery and cancer therapy. Compared to traditional drug delivery systems, nano-based …

Liquid phase oxidation chemistry in continuous-flow microreactors

HPL Gemoets, Y Su, M Shang, V Hessel… - Chemical Society …, 2016 - pubs.rsc.org
Continuous-flow liquid phase oxidation chemistry in microreactors receives a lot of attention
as the reactor provides enhanced heat and mass transfer characteristics, safe use of …

pH-responsive polymer–drug conjugates: design and progress

X Pang, Y Jiang, Q Xiao, AW Leung, H Hua… - Journal of controlled …, 2016 - Elsevier
Polymer–drug conjugates are becoming established as a shining platform for drug delivery.
Incorporation of pH-responsive linker between drug and polymer is expected to realize …

Polymeric conjugates for drug delivery

N Larson, H Ghandehari - Chemistry of Materials, 2012 - ACS Publications
The field of polymer therapeutics has evolved over the past decade and has resulted in the
development of polymer–drug conjugates with a wide variety of architectures and chemical …

Hydrazone linkages in pH responsive drug delivery systems

SJ Sonawane, RS Kalhapure, T Govender - European Journal of …, 2017 - Elsevier
Stimuli-responsive polymeric drug delivery systems using various triggers to release the
drug at the sites have become a major focus area. Among various stimuli-responsive …

Acid-degradable polymers for drug delivery: a decade of innovation

S Binauld, MH Stenzel - Chemical communications, 2013 - pubs.rsc.org
Polymers that start degrading under acidic conditions are increasingly investigated as a
pathway to trigger the release of drugs once the drug carrier reached the slightly acidic …

Cancer nanotheranostics: improving imaging and therapy by targeted delivery across biological barriers

FM Kievit, M Zhang - Advanced materials, 2011 - Wiley Online Library
Cancer nanotheranostics aims to combine imaging and therapy of cancer through use of
nanotechnology. The ability to engineer nanomaterials to interact with cancer cells at the …

Prodrug-based nanoparticulate drug delivery strategies for cancer therapy

C Luo, J Sun, B Sun, Z He - Trends in pharmacological sciences, 2014 - cell.com
Despite the rapid developments in nanotechnology and biomaterials, the efficient delivery of
chemotherapeutic agents is still challenging. Prodrug-based nanoassemblies have many …