Introduction Poly (lactic-co-glycolic acid)(PLGA) has been used in many long-acting drug
formulations, which have been approved by the US Food and Drug Administration (FDA) …

Biopolymeric microparticles have been widely used for long-term release formulations of
short half-life chemicals or synthetic peptides. Characterization of the drug release from …

Background: Tacrolimus (TCR), also known as FK-506, is a biopharmaceutics classification
system (BCS) class II drug that is insoluble in water because of its high log P values. After …

Controlled/sustained delivery systems have been developed rapidly which show the ability
to overcome the obstacles of traditional delivery systems. Daily development of biomedical …

Long-acting injectable (LAI) neuroleptics constitute an effective therapeutical alternative for
individuals suffering from persistent mental illness. These injectable pharmaceuticals help …

Lidocaine, a commonly used local anesthetic, has recently been developed into a number of
ointment products to treat hemorrhoids. This study examined its efficient delivery to the …

In vitro drug release testing is an important quality control tool for formulation development.
However, the literature has evidence that poly-lactide-co-glycolide (PLGA)-based …

Quetiapine myristate (QM), an ester‐bonded lipophilic prodrug of quetiapine (QTP), is
synthesized and converted into an amphiphilic structure in acidic pH to trigger a novel self …

Methods The dimpled-surface on microspheres (MSs) was achieved by oil in water (O/W)
emulsion-solvent evaporation by controlling the stirring rate. The physicochemical properties …

In vitro-in vivo correlation (IVIVC), linking in vitro drug release to in vivo drug release or in
vivo drug absorption, has been explored chiefly for oral extended-release dosage forms …