Genetics of lactose intolerance: an updated review and online interactive world maps of phenotype and genotype frequencies

A Anguita-Ruiz, CM Aguilera, Á Gil - Nutrients, 2020 - mdpi.com
In humans the ability to digest milk lactose is conferred by a β-galactosidase enzyme called
lactase-phlorizin hydrolase (LPH). While in some humans (approximately two-thirds of …

[PDF][PDF] Evolutionary genetics and admixture in African populations

A Pfennig, LN Petersen, P Kachambwa… - Genome Biology and …, 2023 - academic.oup.com
As the ancestral homeland of our species, Africa contains elevated levels of genetic diversity
and substantial population structure. Importantly, African genomes are heterogeneous: They …

Whole-genome sequencing reveals a complex African population demographic history and signatures of local adaptation

S Fan, JP Spence, Y Feng, MEB Hansen, J Terhorst… - Cell, 2023 - cell.com
We conduct high coverage (> 30×) whole-genome sequencing of 180 individuals from 12
indigenous African populations. We identify millions of unreported variants, many predicted …

Decolonising Islamophobia

PF Ejiofor - Ethnic and Racial Studies, 2023 - Taylor & Francis
The predominant conception of Islamophobia defines it as anti-Muslim racism. The
consequence of this rather narrow characterisation is that Islamophobia is treated as a …

[PDF][PDF] Demographic and selection histories of populations across the Sahel/Savannah Belt

C Fortes-Lima, P Tříska, M Čížková… - Molecular biology …, 2022 - academic.oup.com
Abstract The Sahel/Savannah belt harbors diverse populations with different demographic
histories and different subsistence patterns. However, populations from this large African …

Disentangling signatures of selection before and after European colonization in Latin Americans

J Mendoza-Revilla, JC Chacón-Duque… - Molecular biology …, 2022 - academic.oup.com
Throughout human evolutionary history, large-scale migrations have led to intermixing (ie,
admixture) between previously separated human groups. Although classical and recent …

The genomic signatures of natural selection in admixed human populations

S Cuadros-Espinoza, G Laval, L Quintana-Murci… - The American Journal of …, 2022 - cell.com
Admixture has been a pervasive phenomenon in human history, extensively shaping the
patterns of population genetic diversity. There is increasing evidence to suggest that …

Whole genome sequencing reveals signals of adaptive admixture in Creole cattle

S Ben-Jemaa, G Adam, M Boussaha, P Bardou… - Scientific Reports, 2023 - nature.com
Abstract The Creole cattle from Guadeloupe (GUA) are well adapted to the tropical
environment. Its admixed genome likely played an important role in such adaptation. Here …

Whole mitogenomes reveal that NW Africa has acted both as a source and a destination for multiple human movements

J Aizpurua-Iraola, A Abdeli, T Benhassine, F Calafell… - Scientific Reports, 2023 - nature.com
Despite being enclosed between the Mediterranean Sea and the Sahara Desert, North
Africa has been the scenario of multiple human migrations that have shaped the genetic …

Sahelian pastoralism from the perspective of variants associated with lactase persistence

E Priehodová, F Austerlitz, M Čížková… - American Journal of …, 2020 - Wiley Online Library
Objectives Archeological evidence shows that first nomadic pastoralists came to the African
Sahel from northeastern Sahara, where milking is reported by~ 7.5 ka. A second wave of …