Enzyme mimics: advances and applications
E Kuah, S Toh, J Yee, Q Ma… - Chemistry–A European …, 2016 - Wiley Online Library
Enzyme mimics or artificial enzymes are a class of catalysts that have been actively pursued
for decades and have heralded much interest as potentially viable alternatives to natural …
for decades and have heralded much interest as potentially viable alternatives to natural …
Artificial metallonucleases
The development of synthetic agents able to hydrolytically cleave DNA with high efficiency
and selectivity is a fascinating challenge that will show the way to obtaining artificial …
and selectivity is a fascinating challenge that will show the way to obtaining artificial …
DNA Binding Studies of Novel Copper(II) Complexes Containing l-Tryptophan as Chiral Auxiliary: In Vitro Antitumor Activity of Cu−Sn2 Complex in Human …
M Chauhan, K Banerjee, F Arjmand - Inorganic chemistry, 2007 - ACS Publications
Novel trinuclear complexes C23H31N6O6CuSn2Cl5 [1], C23H31N6O6CuZr2Cl5 [2],
C23H31N6O6ZnSn2Cl5 [3], and C23H31N6O6ZnZr2Cl5 [4] were synthesized and …
C23H31N6O6ZnSn2Cl5 [3], and C23H31N6O6ZnZr2Cl5 [4] were synthesized and …
Progress in artificial metallonucleases
The development of synthetic agents able to hydrolytically cleave DNA with high efficiency
and selectivity is still a fascinating challenge. Over the years, many examples have been …
and selectivity is still a fascinating challenge. Over the years, many examples have been …
Artificial metalloenzymes as selective catalysts in aqueous media
J Steinreiber, TR Ward - Coordination Chemistry Reviews, 2008 - Elsevier
The fusion of homogeneous and enzymatic catalysis has recently drawn attention due to
reported novel activities and high selectivities. The incorporation of metal-catalysts into …
reported novel activities and high selectivities. The incorporation of metal-catalysts into …
Artificial DNA cutters for DNA manipulation and genome engineering
Y Aiba, J Sumaoka, M Komiyama - Chemical Society Reviews, 2011 - pubs.rsc.org
This tutorial review provides recent developments in artificial cutters for site-selective
scission of DNA with the focus on chemistry-based DNA cutters. They are useful tools for …
scission of DNA with the focus on chemistry-based DNA cutters. They are useful tools for …
Biological activity and biotechnological aspects of peptide nucleic acid
KE Lundin, L Good, R Strömberg, A Gräslund… - Advances in …, 2006 - Elsevier
During the latest decades a number of different nucleic acid analogs containing natural
nucleobases on a modified backbone have been synthesized. An example of this is peptide …
nucleobases on a modified backbone have been synthesized. An example of this is peptide …
DNA‐Targeted Metallodrugs: An Untapped Source of Artificial Gene Editing Technology
DNA binding metal complexes are synonymous with anticancer drug discovery. Given the
array of structural and chemical reactivity properties available through careful design, metal …
array of structural and chemical reactivity properties available through careful design, metal …
Molecular drug design, synthesis and crystal structure determination of CuII–SnIV heterobimetallic core: DNA binding and cleavage studies
A novel heterobimetallic CuII–SnIV complex 1 bearing bioactive 1, 10-phenanthroline
pharmacophore ligand scaffold was synthesized and characterized by elemental analysis …
pharmacophore ligand scaffold was synthesized and characterized by elemental analysis …
Peptide nucleic acids (PNAs), a chemical overview
A Porcheddu, G Giacomelli - Current medicinal chemistry, 2005 - ingentaconnect.com
Peptide nucleic acid (PNA) is a nucleic acid analogue and a fully synthetic DNA/RNA-
recognising ligand with a neutral peptide-like backbone. In spite of the large change on the …
recognising ligand with a neutral peptide-like backbone. In spite of the large change on the …