Fish, docosahexaenoic acid and Alzheimer's disease

SC Cunnane, M Plourde, F Pifferi, M Bégin… - Progress in lipid …, 2009 - Elsevier
Cognitive decline in the elderly, particularly Alzheimer's disease (AD), is a major socio-
economic and healthcare concern. We review here the literature on one specific aspect of …

Omega‐3 fatty acids in early prevention of inflammatory neurodegenerative disease: A focus on Alzheimer's disease

J Thomas, CJ Thomas, J Radcliffe… - BioMed research …, 2015 - Wiley Online Library
Alzheimer's disease (AD) is the leading cause of dementia and the most common
neurodegenerative disease in the elderly. Furthermore, AD has provided the most positive …

Determinants of erythrocyte omega‐3 fatty acid content in response to fish oil supplementation: a dose–response randomized controlled trial

MR Flock, AC Skulas‐Ray, WS Harris… - Journal of the …, 2013 - Am Heart Assoc
Background The erythrocyte membrane content of eicosapentaenoic acid (EPA) and
docosahexaenoic acid (DHA), which constitutes the omega‐3 index (O3I), predicts …

[HTML][HTML] Towards establishing dietary reference intakes for eicosapentaenoic and docosahexaenoic acids

WS Harris, D Mozaffarian, M Lefevre, CD Toner… - The Journal of …, 2009 - Elsevier
There is considerable interest in the impact of (n-3) long-chain PUFA in mitigating the
morbidity and mortality caused by chronic diseases. In 2002, the Institute of Medicine …

Lipid alterations in lipid rafts from Alzheimer's disease human brain cortex

V Martín, N Fabelo, G Santpere, B Puig… - Journal of …, 2010 - content.iospress.com
Lipid rafts are membrane microdomains intimately associated with cell signaling. These
biochemical microstructures are characterized by their high contents of sphingolipids …

High-fat diet aggravates amyloid-beta and tau pathologies in the 3xTg-AD mouse model

C Julien, C Tremblay, A Phivilay, L Berthiaume… - Neurobiology of …, 2010 - Elsevier
To investigate potential dietary risk factors of Alzheimer's disease (AD), triple transgenic
(3xTg-AD) mice were exposed from 4 to 13 months of age to diets with a low n-3: n-6 …

Oxidative stress and cell membranes in the pathogenesis of Alzheimer's disease

PH Axelsen, H Komatsu, IVJ Murray - Physiology, 2011 - journals.physiology.org
Amyloid β proteins and oxidative stress are believed to have central roles in the
development of Alzheimer's disease. Lipid membranes are among the most vulnerable …

Dietary omega 3 polyunsaturated fatty acids and Alzheimer's disease: interaction with apolipoprotein E genotype

P Barberger-Gateau, C Samieri… - Current Alzheimer …, 2011 - ingentaconnect.com
Epidemiological studies suggest a protective role of omega-3 poly-unsaturated fatty acids (n-
3 PUFA) against Alzheimer's disease (AD). However, most intervention studies of …

[图书][B] Fat detection: taste, texture, and post ingestive effects

JP Montmayeur, J Le Coutre - 2009 - taylorfrancis.com
Presents the State-of-the-Art in Fat Taste TransductionA bite of cheese, a few potato chips, a
delectable piece of bacon-a small taste of high-fat foods often draws you back for more. But …

[HTML][HTML] Role of docosahexaenoic acid in the modulation of glial cells in Alzheimer's disease

D Heras-Sandoval, J Pedraza-Chaverri… - Journal of …, 2016 - Springer
Docosahexaenoic acid (DHA) is an omega-3 (ω-3) long-chain polyunsaturated fatty acid
(LCPUFA) relevant for brain function. It has largely been explored as a potential candidate to …