Psychedelics in psychiatry: neuroplastic, immunomodulatory, and neurotransmitter mechanisms

A Inserra, D De Gregorio, G Gobbi - Pharmacological Reviews, 2021 - ASPET
Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …

Prevalencia, causas y tratamiento de la depresión Mayor

EA Pérez-Padilla, VM Cervantes-Ramírez… - Revista …, 2017 - scielo.org.mx
La depresión mayor representa un problema de salud pública debido a su alta prevalencia.
La etiología de la depresión es compleja ya que en ella intervienen factores psicosociales …

BDNF as a biomarker for successful treatment of mood disorders: a systematic & quantitative meta-analysis

M Polyakova, K Stuke, K Schuemberg, K Mueller… - Journal of affective …, 2015 - Elsevier
Background Peripheral brain-derived neurotrophic factor (BDNF) is decreased in acute
major depressive disorder (MDD) and bipolar disorder (BD) and recovered after treatment …

How microbes affect depression: underlying mechanisms via the Gut–brain axis and the modulating role of probiotics

K Suda, K Matsuda - International journal of molecular sciences, 2022 - mdpi.com
Accumulating evidence suggests that the gut microbiome influences the brain functions and
psychological state of its host via the gut–brain axis, and gut dysbiosis has been linked to …

Anxiolytic and antidepressive potentials of rosmarinic acid: A review with a focus on antioxidant and anti-inflammatory effects

A Dahchour - Pharmacological Research, 2022 - Elsevier
Depression and anxiety are the most prevalent neuropsychiatric disorders that have
emerged as global health concerns. Anxiolytic and antidepressant drugs, such as …

A neurotrophic model for stress-related mood disorders

RS Duman, LM Monteggia - Biological psychiatry, 2006 - Elsevier
There is a growing body of evidence demonstrating that stress decreases the expression of
brain-derived neurotrophic factor (BDNF) in limbic structures that control mood and that …

Molecular mechanisms of depression: perspectives on new treatment strategies

UE Lang, S Borgwardt - Cellular Physiology and Biochemistry, 2013 - karger.com
Depression is a multicausal disorder and has been associated with the risk to develop
cancer, dementia, diabetes, epilepsy and stroke. As a metabolic disorder depression has …

Biomarkers of post-COVID depression

P Lorkiewicz, N Waszkiewicz - Journal of Clinical medicine, 2021 - mdpi.com
The COVID-19 pandemic is spreading around the world and 187 million people have
already been affected. One of its after-effects is post-COVID depression, which, according to …

A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression

AR Brunoni, M Lopes, F Fregni - International Journal of …, 2008 - academic.oup.com
Several clinical studies on major depressive disorder (MDD) have shown that blood brain-
derived neurotrophic factor (BDNF)–a factor used to index neuroplasticity–is associated with …

Functional biomarkers of depression: diagnosis, treatment, and pathophysiology

HD Schmidt, RC Shelton, RS Duman - Neuropsychopharmacology, 2011 - nature.com
Major depressive disorder (MDD) is a heterogeneous illness for which there are currently no
effective methods to objectively assess severity, endophenotypes, or response to treatment …