Despite having been identified as the organism that causes tuberculosis in 1882,
Mycobacterium tuberculosis has managed to still evade our understanding of the protective …

Mycobacterium tuberculosis is a leading cause of mortality worldwide and establishes a
long-lived latent infection in a substantial proportion of the human population. Multiple lines …

Mycobacterium tuberculosis (Mtb) is the leading cause of death from infection worldwide.
The only available vaccine, BCG (Bacillus Calmette–Guérin), is given intradermally and has …

While a third of the world carries the burden of tuberculosis, disease control has been
hindered by a lack of tools, including a rapid, point-of-care diagnostic and a protective …

Mycobacterium tuberculosis lung infection results in a complex multicellular structure: the
granuloma. In some granulomas, immune activity promotes bacterial clearance, but in …

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), is a global cause of death.
Granuloma-associated lymphoid tissue (GrALT) correlates with protection during TB, but the …

Mycobacterium tuberculosis, the etiological agent of tuberculosis (TB), is an extremely
successful pathogen that adapts to survive within the host. During the latency phase of …

The role of Igs in natural protection against infection by Mycobacterium tuberculosis (Mtb),
the causative agent of TB, is controversial. Although passive immunization with mAbs …

Tuberculosis is a far-reaching, high-impact disease. It is among the top ten causes of death
worldwide caused by a single infectious agent; 1.6 million tuberculosis-related deaths were …

Human Mycobacterium tuberculosis infection was thought to result in either active
symptomatic tuberculosis (TB) or latent asymptomatic infection. It is now clear that this binary …