[HTML][HTML] Development and maintenance of vision's first synapse

CA Burger, D Jiang, RD Mackin, MA Samuel - Developmental biology, 2021 - Elsevier
Synapses in the outer retina are the first information relay points in vision. Here,
photoreceptors form synapses onto two types of interneurons, bipolar cells and horizontal …

Progenitor division and cell autonomous neurosecretion are required for rod photoreceptor sublaminar positioning

A Gurdita, VQB Pham Truong, P Dolati… - Proceedings of the …, 2023 - National Acad Sciences
Migration is essential for the laminar stratification and connectivity of neurons in the central
nervous system. In the retina, photoreceptors (PRs) migrate to positions according to …

Critical role of the presynaptic protein CAST in maintaining the photoreceptor ribbon synapse triad

A Hagiwara, A Mizutani, S Kawamura, M Abe… - International journal of …, 2023 - mdpi.com
The cytomatrix at the active zone-associated structural protein (CAST) and its homologue,
named ELKS, being rich in glutamate (E), leucine (L), lysine (K), and serine (S), belong to a …

A Picture Worth a Thousand Molecules—Integrative Technologies for Mapping Subcellular Molecular Organization and Plasticity in Developing Circuits

JA Minehart, CM Speer - Frontiers in Synaptic Neuroscience, 2021 - frontiersin.org
A key challenge in developmental neuroscience is identifying the local regulatory
mechanisms that control neurite and synaptic refinement over large brain volumes …

Sensory neuron LKB1 mediates ovarian and reproductive function

ME Lenert, EK Debner, MD Burton - Scientific Reports, 2024 - nature.com
Treatments for reproductive disorders in women consist of hormone replacement therapy,
which have negative side effects that impact health, spurring the need to understand new …

LKB1 and AMPK instruct cone nuclear position to modify visual function

CA Burger, NE Albrecht, D Jiang, JH Liang, RA Poché… - Cell reports, 2021 - cell.com
Cone photoreceptors detect light and are responsible for color vision. These cells display a
distinct polarized morphology where nuclei are precisely aligned in the apical retina …

Functional Analysis of Axon Guidance Programs in Developmental Photoreceptor Connectivity

VQBP Truong - 2024 - search.proquest.com
Vision depends on the light sensing neurons of the retina: rod and cone photoreceptors.
Neurons in the mammalian retina cannot regenerate, therefore, photoreceptor degeneration …

Toward Ultra-Resolution Biomolecular Mapping in Cells with Expansion Microscopy

Y Liu - 2024 - dspace.mit.edu
To investigate the molecular and cellular foundations of biological functions, achieving
nanoscale spatial resolution in biomolecular imaging is essential. Expansion microscopy …

[图书][B] Development, Adaptation, and Persistent, Stimulus-Independent Neural Activity in a Sensorimotor Circuit in Drosophila melanogaster

BW McFarland - 2022 - search.proquest.com
Central to all animals is the ability to interpret relevant external stimuli and react
appropriately. For animals to be able to recognize and react appropriately to stimuli, neurons …

[图书][B] Genetic Regulation of Retinal Development

B Kulesh - 2022 - search.proquest.com
The development of the central nervous system (CNS), which includes the brain, requires
the coordination of numerous intricate processes. Due to its complexity, the brain can be a …