Chronic kidney disease

AC Webster, EV Nagler, RL Morton, P Masson - The lancet, 2017 - thelancet.com
The definition and classification of chronic kidney disease (CKD) have evolved over time,
but current international guidelines define this condition as decreased kidney function …

Global prevalence of chronic kidney disease–a systematic review and meta-analysis

NR Hill, ST Fatoba, JL Oke, JA Hirst, CA O'Callaghan… - PloS one, 2016 - journals.plos.org
Chronic kidney disease (CKD) is a global health burden with a high economic cost to health
systems and is an independent risk factor for cardiovascular disease (CVD). All stages of …

Target risk factors for dementia prevention: a systematic review and Delphi consensus study on the evidence from observational studies

K Deckers, MPJ van Boxtel… - … journal of geriatric …, 2015 - Wiley Online Library
Objective Dementia has a multifactorial etiology, but the importance of individual health and
lifestyle related risk factors is often uncertain or based on few studies. The goal of this paper …

Cardiovascular risk factors and future risk of Alzheimer's disease

RFAG de Bruijn, MA Ikram - BMC medicine, 2014 - Springer
Alzheimer's disease (AD) is the most common neurodegenerative disorder in elderly people,
but there are still no curative options. Senile plaques and neurofibrillary tangles are …

Stroke and cerebrovascular diseases in patients with chronic kidney disease

K Toyoda, T Ninomiya - The Lancet Neurology, 2014 - thelancet.com
Chronic kidney disease, defined as a reduced glomerular filtration rate or increased urinary
albumin excretion, is recognised as a rapidly growing global health burden, and increasing …

Chronotherapy for hypertension

NP Bowles, SS Thosar, MX Herzig, SA Shea - Current hypertension …, 2018 - Springer
Abstract Purpose of Review Given the emerging knowledge that circadian rhythmicity exists
in every cell and all organ systems, there is increasing interest in the possible benefits of …

Peripheral clearance of brain-derived Aβ in Alzheimer's disease: pathophysiology and therapeutic perspectives

Y Cheng, DY Tian, YJ Wang - Translational neurodegeneration, 2020 - Springer
Alzheimer's disease (AD) is the most common type of dementia, and no disease-modifying
treatments are available to halt or slow its progression. Amyloid-beta (Aβ) is suggested to …

Cognition in chronic kidney disease: a systematic review and meta-analysis

I Berger, S Wu, P Masson, PJ Kelly, FA Duthie… - BMC medicine, 2016 - Springer
Background Cognitive impairment is common in people with chronic kidney disease (CKD)
and associated with increased morbidity and mortality. Subtle changes can impact …

Kidney function, kidney function decline, and the risk of dementia in older adults: a registry-based study

H Xu, S Garcia-Ptacek, M Trevisan, M Evans… - Neurology, 2021 - AAN Enterprises
Objective Community-based reports regarding the association between the estimated
glomerular filtration rate (eGFR) and dementia risk show conflicting results. The aim of this …

Homocysteine and age-associated disorders

EA Ostrakhovitch, S Tabibzadeh - Ageing research reviews, 2019 - Elsevier
There are numerous theories of aging, a process which still seems inevitable. Aging leads to
cancer and multi-systemic disorders as well as chronic diseases. Decline in age-associated …